Title:
NOVEL PYRIMIDINE SULFONAMIDE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2021/029450
Kind Code:
A1
Abstract:
The present invention relates to: a pyrimidine sulfonamide derivative disubstituted at a specific position with a trifluoroethoxy group; and a pharmaceutical composition which is for preventing or treating cancer and comprises same as an active ingredient. A compound, having favorably improved CD73 inhibitory activity, metabolic stability, and longevity of drug efficacy, and thus increased usefulness as an anticancer drug, can be provided by introducing a trifluoroethoxy group to pyrimidine sulfonamide.
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Inventors:
LEE CHANG HOON (KR)
PARK SEONG JUN (KR)
PARK SEONG JUN (KR)
Application Number:
PCT/KR2019/010182
Publication Date:
February 18, 2021
Filing Date:
August 12, 2019
Export Citation:
Assignee:
KOREA RES INST CHEMICAL TECH (KR)
International Classes:
C07D239/60; C07D403/12; C07D405/12
Domestic Patent References:
| WO2018167276A1 | 2018-09-20 | |||
| WO2018017858A1 | 2018-01-25 | |||
| WO2014139325A1 | 2014-09-18 |
Foreign References:
| US20090286782A1 | 2009-11-19 | |||
| KR20050055415A | 2005-06-13 |
Attorney, Agent or Firm:
GHONG-GAN INTERNATIONAL PATENT LAW FIRM (KR)
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