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Patent Searching and Data


Title:
NOVEL RECOMBINANT TYROSINASE
Document Type and Number:
WIPO Patent Application WO/2018/124623
Kind Code:
A1
Abstract:
The present invention relates to a novel recombinant tyrosinase produced by newly redesigning a gene on the basis of a tyrosinase present in marine polar ammonia oxidation-related bacteria. Unlike conventionally known tyrosinases, the recombinant tyrosinase of the present invention can be very easily mass-produced from a transformant and, unlike conventional enzymes, can efficiently perform reactions over a wide pH range and at room temperature and low temperature. Therefore, the recombinant tyrosinase of the present invention can be variously utilized in the production of functional medicines and biomaterials, both of which contain phenolic compounds, and can be utilized in various industrial fields requiring catalytic reactions using tyrosinases, such as bioremediation processes of toxic phenolic compounds, which are harmful to the environment.

Inventors:
CHOI YOO SEONG (KR)
DO HYUN SU (KR)
Application Number:
PCT/KR2017/015183
Publication Date:
July 05, 2018
Filing Date:
December 21, 2017
Export Citation:
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Assignee:
THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIV (KR)
International Classes:
C12N9/02
Foreign References:
KR20160123088A2016-10-25
KR20100105256A2010-09-29
KR20120114072A2012-10-16
KR20080030550A2008-04-04
Other References:
DATABASE Protein 18 June 2014 (2014-06-18), "MULTISPECIES: tyrosinase [Nitrosopumilus]", XP055607296, retrieved from NCBI Database accession no. WP_014962752.1
DO, HYUNSU: "A tyrosinase, mTyr-CNK, that is functionally available as a monophenol monooxygenase", SCIENTIFIC REPORTS, vol. 7, no. 1, 17267, 8 December 2017 (2017-12-08), pages 1 - 8, XP055607290
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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