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Patent Searching and Data


Title:
NOVEL THERAPEUTIC AGENT FOR VASCULAR DISORDER
Document Type and Number:
WIPO Patent Application WO/2021/225149
Kind Code:
A1
Abstract:
Provided is a medical agent for effectively treating a vascular disorder caused by the excessive synthesis and secretion of type IV collagen protein from vascular endothelial cells. Provided are [1] a therapeutic agent for a vascular disorder associated with the excessive synthesis and secretion of type IV collagen protein, [2] a therapeutic agent for diseases caused by the excessive synthesis and secretion of type IV collagen protein, [3] a pharmaceutical composition for treating a vascular disorder associated with the excessive synthesis and secretion of type IV collagen protein, [4] a pharmaceutical composition for treating diseases caused by the excessive synthesis and secretion of type IV collagen protein from vascular endothelial cells, and [5] an agent for inhibiting the excessive synthesis and secretion of type IV collagen protein from vascular endothelial cells, each of which contains sirolimus as an active ingredient.

Inventors:
ERA TAKUMI (JP)
WATANABE SAYAKA (JP)
KUSAYANAGI TOMOE (JP)
Application Number:
PCT/JP2021/017423
Publication Date:
November 11, 2021
Filing Date:
May 07, 2021
Export Citation:
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Assignee:
UNIV KUMAMOTO NAT UNIV CORP (JP)
International Classes:
A61P1/00; A61K31/439; A61P9/00; A61P9/12; A61P9/14; A61P11/00; A61P13/12; A61P43/00
Domestic Patent References:
WO2012105521A12012-08-09
Foreign References:
US20140037548A12014-02-06
CN102499919A2012-06-20
US20100166869A12010-07-01
Attorney, Agent or Firm:
TANAKA, Yasuko (JP)
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