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Title:
NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS WITH EXTENDED LIPOPHILIC SIDE CHAINS
Document Type and Number:
WIPO Patent Application WO/2019/185938
Kind Code:
A3
Abstract:
The present invention is directed towards the use of substituted chroman-6- ols with extended lipophilic side chains of formula (I) wherein one of the two substituents R1 and R2 is C12-21-alkyl and the other of the two substituents R1 and R2 is either hydrogen or C1-5-alkyl or (CH2)n-OH with n being an integer from 1 to 5, and wherein A is CH(R3), and wherein R3, R4 and R6 are independently from each other H or C1-4-alkyl, and wherein R5 is H or OH or C1-4-alkyl or C1-4-alkoxy; with the proviso that at least two of R4, R5 and R6 are not methyl, when R3 is H and one of the substituents R1 and R2 is methyl and the other of the two substituents R1 and R2 is C12-21-alkyl, as antioxidants, especially in feed such as pet food and feed ingredients such as fish meal, insect meal and poultry meal, as well as PUFA-containing oil such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil. The present invention is further directed towards feed ingredients and feed for insects, aquatic and terrestrial animals comprising such substituted chroman-6-ols with extended lipophilic side chains of formula (I).

Inventors:
CLASADONTE LAURE (CH)
DUESTERLOH ANDRÉ (CH)
INDRASENA WEERASINGHE (CH)
NETSCHER THOMAS (CH)
STEMMLER RENÉ (CH)
Application Number:
PCT/EP2019/058117
Publication Date:
November 07, 2019
Filing Date:
March 29, 2019
Export Citation:
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Assignee:
DSM IP ASSETS BV (NL)
International Classes:
C07D311/72
Domestic Patent References:
WO2011153353A12011-12-08
WO2003101950A22003-12-11
Foreign References:
KR20150142152A2015-12-22
Other References:
TRES, A. ET AL.: "Impact of the oxidative quality of fish oils in feeds on the composition and oxidative stability of chicken and rabbit meat", ANIMAL FEED SCIENCE AND TECHNOLOGY, vol. 196, 2014, pages 76 - 87, XP002790996
LACHMAN, J. ET AL.: "Towards complex utilisation of winemaking residues: Characterisation of grape seeds by total phenols, tocols and essential elements content as a by-product of winemaking", INDUSTRIAL CROPS AND PRODUCTS, vol. 49, 2013, pages 445 - 453, XP002790997
MORALES PATRICIA ET AL: "Non-fermented and fermented jabuticaba (Myrciaria caulifloraMart.) pomaces as valuable sources of functional ingredients", FOOD CHEMISTRY, ELSEVIER LTD, NL, vol. 208, 6 April 2016 (2016-04-06), pages 220 - 227, XP029527356, ISSN: 0308-8146, DOI: 10.1016/J.FOODCHEM.2016.04.011
ALAMGIR ED - ALAMGIR A N M: "Vitamins, nutraceuticals, food, additives, enzymes, anesthetic acids and comsetics", 1 January 2018 (2018-01-01), XP009512903, ISSN: 0071-786X, Retrieved from the Internet [retrieved on 20180624]
Attorney, Agent or Firm:
STECK, Melanie (CH)
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