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Title:
NUCLEIC ACID ANTIGENS EMBEDDED IN THERMOPLASTIC
Document Type and Number:
WIPO Patent Application WO2004070006
Kind Code:
A3
Abstract:
An assay device is made by combining a polynucleic acid with a molten material capable of solidifying into a solid thermoplastic or thermosetting material and then allowing the molten material to solidify. The thus-formed thermoplastic solid material has at least some molecules of the polynucleic acid exposed on the surface of the thermoplastic solid material in an orientation wherein the polynucleic acid is bindable to a binding partner by specific binding. The invention further relates to a solid phase substrate having a polynucleic acid embedded therein. The invention further relates to the use of a solid phase substrate having a polynucleic acid embedded therein for hybridization assays and immunoassays to detect anti-nucleic acid antibodies.

Inventors:
MCINTYRE JOHN (US)
Application Number:
PCT/US2004/002542
Publication Date:
November 17, 2005
Filing Date:
January 30, 2004
Export Citation:
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Assignee:
EMBEDDED CONCEPTS LLC (US)
MCINTYRE JOHN (US)
International Classes:
C07H21/00; C12N1/00; C12N15/10; C12N15/11; C12Q1/68; G01N33/53; G01N33/543; G01N33/564; G01N33/92; C12N; (IPC1-7): C07H21/00; C12N15/10; C12N15/11; C12Q1/68; G01N33/53
Domestic Patent References:
WO1999008113A11999-02-18
Foreign References:
US6177282B12001-01-23
Other References:
See also references of EP 1590439A4
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