Title:
NUCLEIC ACID COMPLEX AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2021/153687
Kind Code:
A1
Abstract:
Disclosed is a nucleic acid complex represented by formula (I) or a pharmaceutically acceptable salt thereof (X is CH2 or O; Y is a sugar ligand having mannose or GalNac; n is an integer of 1 to 8; and Z is a group containing an oligonucleotide).
Inventors:
SUZUKI YUTA (JP)
YAMAZAKI KAZUTO (JP)
KUBARA KENJI (JP)
TAMURA TOMOHIKO (JP)
KUROTAKI DAISUKE (JP)
YAMAZAKI KAZUTO (JP)
KUBARA KENJI (JP)
TAMURA TOMOHIKO (JP)
KUROTAKI DAISUKE (JP)
Application Number:
PCT/JP2021/003085
Publication Date:
August 05, 2021
Filing Date:
January 28, 2021
Export Citation:
Assignee:
EISAI R&D MAN CO LTD (JP)
International Classes:
C07K9/00; A61K31/7088; A61K47/54; A61K48/00; C12N15/113
Domestic Patent References:
| WO2018140920A1 | 2018-08-02 | |||
| WO2015042447A1 | 2015-03-26 | |||
| WO2018187515A1 | 2018-10-11 | |||
| WO2009073809A2 | 2009-06-11 | |||
| WO2014179620A1 | 2014-11-06 | |||
| WO2016100401A1 | 2016-06-23 | |||
| WO2018004004A1 | 2018-01-04 | |||
| WO2013075035A1 | 2013-05-23 | |||
| WO2015105083A1 | 2015-07-16 |
Foreign References:
| JP2016526874A | 2016-09-08 |
Other References:
NATURE REVIEWS DRUG DISCOVERY, vol. 8, 2009, pages 129 - 138
J.AM. CHEM. SOC., vol. 136, 2014, pages 16958 - 16961
NUCLEIC ACIDS RESEARCH, vol. 47, no. 3, 2019, pages 1082 - 1096
See also references of EP 4071163A4
J.AM. CHEM. SOC., vol. 136, 2014, pages 16958 - 16961
NUCLEIC ACIDS RESEARCH, vol. 47, no. 3, 2019, pages 1082 - 1096
See also references of EP 4071163A4
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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