Title:
NUCLEOTIDE DERIVATIVE, PHARMACEUTICAL COMPOSITE THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/166581
Kind Code:
A1
Abstract:
A nucleotide derivative, a pharmaceutical composition thereof, and a use thereof. Specifically disclosed are a nucleotide derivative represented by formula (I) or a tautomer, a stereoisomer, a solvate, a pharmaceutically acceptable salt thereof, and an application thereof in the preparation of a drug for treating cardiovascular and cerebrovascular diseases, wherein the definition of groups in formula (I) is detailed in the description.
Inventors:
ZHANG ZHEFENG (CN)
HOU WEN (CN)
MENG YUELEI (CN)
LI HAIDE (CN)
HOU WEN (CN)
MENG YUELEI (CN)
LI HAIDE (CN)
Application Number:
PCT/CN2022/072689
Publication Date:
August 11, 2022
Filing Date:
January 19, 2022
Export Citation:
Assignee:
SHIJIAZHUANG DISCOVERY MEDICINE TECH CO LTD (CN)
International Classes:
C07H19/23; A61K31/135; A61K31/165; A61K31/706; A61P7/00; A61P31/12; A61P31/14
Domestic Patent References:
| WO2021202907A2 | 2021-10-07 | |||
| WO2021262826A2 | 2021-12-30 |
Foreign References:
| CN108348526A | 2018-07-31 | |||
| CN107073005A | 2017-08-18 | |||
| CN103052631A | 2013-04-17 | |||
| CN110724174A | 2020-01-24 | |||
| US20180030080A1 | 2018-02-01 | |||
| CN102348712A | 2012-02-08 | |||
| US5763596A | 1998-06-09 | |||
| CN111542531A | 2020-08-14 | |||
| CN101384609A | 2009-03-11 | |||
| US20120020921A1 | 2012-01-26 | |||
| US20210284670A1 | 2021-09-16 | |||
| CN113292567A | 2021-08-24 |
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