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Title:
ORAL DRUG DOSAGE FORMS FOR STOMACH RETENTION
Document Type and Number:
WIPO Patent Application WO/2024/083145
Kind Code:
A1
Abstract:
Provided herein are drug dosage forms designed to provide a desired retention in an individual based on geometric differences between a pre-administration and post-administration state of the dosage form. In certain aspects, provided are oral drug dosage forms comprising a swellable and expandable material configured, upon swelling or expanding, to drive expansion of the overall size of the oral drug dosage forms such that the oral drug dosage forms are retained in the stomach for a desired period of time. In certain other aspects, provided is directed to components useful for the oral drug dosage forms taught herein. In certain other aspects, provided is directed to methods of designing, methods of making, such as involving three-dimensional (3D) printing, injection molding, ultrasonic welding, or any combination thereof, commercial batches, and methods of delivering a drug to an individual comprising administering an oral drug dosage form taught herein.

Inventors:
ZUO XIANGHAO (CN)
DENG FEIHUANG (CN)
LUO QING (CN)
YANG PEIZHAN (CN)
LIU FUQIANG (CN)
ZHAO ANG (CN)
ZHANG RURU (CN)
LI XIAOLING (US)
CHENG SENPING (CN)
Application Number:
PCT/CN2023/125190
Publication Date:
April 25, 2024
Filing Date:
October 18, 2023
Export Citation:
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Assignee:
TRIASTEK INC (CN)
International Classes:
A61K9/22; A61K9/24
Domestic Patent References:
WO2022089631A12022-05-05
WO2015187746A12015-12-10
WO2022089588A12022-05-05
Foreign References:
US20180250226A12018-09-06
US20200146979A12020-05-14
US20210106799A12021-04-15
US20220031624A12022-02-03
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
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