Title:
OVARIAN CANCER BIOMARKER AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/056199
Kind Code:
A1
Abstract:
A biomarker, a method and a test kit, being used for identifying and screening for ovarian cancer and to monitor the treatment of ovarian cancer.
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Inventors:
TORNG PAO-LING (CN)
TSAY YEOU-GUANG (CN)
SHEN JENTA (CN)
CHOW SONG-NAN (CN)
CHIEN CHIN-HSIANG (CN)
TSAY YEOU-GUANG (CN)
SHEN JENTA (CN)
CHOW SONG-NAN (CN)
CHIEN CHIN-HSIANG (CN)
Application Number:
PCT/CN2017/102407
Publication Date:
March 28, 2019
Filing Date:
September 20, 2017
Export Citation:
Assignee:
ONCOLOCK CO LTD (CN)
International Classes:
C12Q1/68; G01N33/574
Domestic Patent References:
| WO2006034032A2 | 2006-03-30 | |||
| WO1987004462A1 | 1987-07-30 |
Foreign References:
| CN102851388A | 2013-01-02 | |||
| CN102654502A | 2012-09-05 | |||
| US5565332A | 1996-10-15 | |||
| US5580717A | 1996-12-03 | |||
| US5733743A | 1998-03-31 | |||
| US6265150B1 | 2001-07-24 | |||
| US4946778A | 1990-08-07 | |||
| US4704692A | 1987-11-03 |
Other References:
YAO, ZHENGLIANG: "Proteomics Approach to Identify Serum Glycoproteins as Biomarkers in Human Lung Adenocarcinoma", DISSERTATION, 26 November 2007 (2007-11-26), pages 1 - 63, XP009517915
PALARASAH, Y. ET AL.: "Generation of a C3c Specific Monoclonal Antibody and Assessment of C3c as a Putative Inflammatory Marker Derived from Complement Factor C3", JOURNAL OF IMMUNOLOGICAL METHODS, vol. 362, no. 1-2, 24 September 2010 (2010-09-24), pages 142 - 150, XP027509601, DOI: 10.1016/j.jim.2010.09.024
KABBAGE, M. ET AL.: "Protein Alterations in Infiltrating Ductal Carcinomas of the Breast as Detected by Nonequilibrium pH Gradient Electrophoresis and Mass Spectrometry", JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, vol. 2008, 31 December 2008 (2008-12-31), pages 1 - 10, XP055317383
WEN, C.L. ET AL.: "Development of an AlphaLISA Assay to Quantify Serum Core-fucosylated E-cadherin as a Metastatic Lung Adenocarcinoma Biomarker", JOURNAL OF PROTEOMICS, vol. 75, no. 13, 23 May 2012 (2012-05-23), pages 3963 - 3976, XP028497081, DOI: 10.1016/j.jprot.2012.05.015
GAN, HUI ET AL.: "Advance in Researches on the Third Component of Complement(C3)", FOREIGN MEDICAL SCIENCES (SECTION OF CLINICAL BIOCHEMISTRY AND LABORATORY MEDICINE), vol. 25, no. 6, 30 November 2004 (2004-11-30), pages 519 - 521, XP009517892, ISSN: 1673-4130
MOORE RG. ET AL., CURR OPIN. ONCOL., vol. 22, no. 5, September 2010 (2010-09-01), pages 492 - 7
HELLSTROM I. ET AL., CANCER RESEARCH, vol. 63, 1 July 2003 (2003-07-01), pages 3695 - 3700
ROSEN DCX ET AL., GYNECOLOGIC ONCOLOGY, vol. 99, no. 2, November 2005 (2005-11-01), pages 255 - 526
HARLOWLANE: "Antibodies: A Laboratory Manual", 1988, COLD SPRING HARBOR LABORATORY
KOHLER, B.MILSTEIN, C., NATURE, vol. 256, 1975, pages 495 - 497
BUCK, D.W. ET AL., IN VITRO, vol. 18, 1982, pages 377 - 381
WINTER ET AL., ANNU. REV. IMMUNOL., vol. 12, 1994, pages 433 - 455
MCCAFFERTY ET AL., NATURE, vol. 348, 1990, pages 552 - 553
MORRISON ET AL., PROC. NAT. ACAD. SCI., vol. 81, 1984, pages 6851
MORRISON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 81, 1984, pages 6851
NEUBERGER ET AL., NATURE, vol. 314, 1984, pages 452
QUEEN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 10029 - 10033
HARLOWLANE: "Using Antibodies", 1999, LABORATORY MANUAL, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3686286A4
PALARASAH, Y. ET AL.: "Generation of a C3c Specific Monoclonal Antibody and Assessment of C3c as a Putative Inflammatory Marker Derived from Complement Factor C3", JOURNAL OF IMMUNOLOGICAL METHODS, vol. 362, no. 1-2, 24 September 2010 (2010-09-24), pages 142 - 150, XP027509601, DOI: 10.1016/j.jim.2010.09.024
KABBAGE, M. ET AL.: "Protein Alterations in Infiltrating Ductal Carcinomas of the Breast as Detected by Nonequilibrium pH Gradient Electrophoresis and Mass Spectrometry", JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, vol. 2008, 31 December 2008 (2008-12-31), pages 1 - 10, XP055317383
WEN, C.L. ET AL.: "Development of an AlphaLISA Assay to Quantify Serum Core-fucosylated E-cadherin as a Metastatic Lung Adenocarcinoma Biomarker", JOURNAL OF PROTEOMICS, vol. 75, no. 13, 23 May 2012 (2012-05-23), pages 3963 - 3976, XP028497081, DOI: 10.1016/j.jprot.2012.05.015
GAN, HUI ET AL.: "Advance in Researches on the Third Component of Complement(C3)", FOREIGN MEDICAL SCIENCES (SECTION OF CLINICAL BIOCHEMISTRY AND LABORATORY MEDICINE), vol. 25, no. 6, 30 November 2004 (2004-11-30), pages 519 - 521, XP009517892, ISSN: 1673-4130
MOORE RG. ET AL., CURR OPIN. ONCOL., vol. 22, no. 5, September 2010 (2010-09-01), pages 492 - 7
HELLSTROM I. ET AL., CANCER RESEARCH, vol. 63, 1 July 2003 (2003-07-01), pages 3695 - 3700
ROSEN DCX ET AL., GYNECOLOGIC ONCOLOGY, vol. 99, no. 2, November 2005 (2005-11-01), pages 255 - 526
HARLOWLANE: "Antibodies: A Laboratory Manual", 1988, COLD SPRING HARBOR LABORATORY
KOHLER, B.MILSTEIN, C., NATURE, vol. 256, 1975, pages 495 - 497
BUCK, D.W. ET AL., IN VITRO, vol. 18, 1982, pages 377 - 381
WINTER ET AL., ANNU. REV. IMMUNOL., vol. 12, 1994, pages 433 - 455
MCCAFFERTY ET AL., NATURE, vol. 348, 1990, pages 552 - 553
MORRISON ET AL., PROC. NAT. ACAD. SCI., vol. 81, 1984, pages 6851
MORRISON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 81, 1984, pages 6851
NEUBERGER ET AL., NATURE, vol. 314, 1984, pages 452
QUEEN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 10029 - 10033
HARLOWLANE: "Using Antibodies", 1999, LABORATORY MANUAL, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3686286A4
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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