Title:
OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/002078
Kind Code:
A1
Abstract:
The present invention relates to the fields of pharmaceutical chemistry and pharmacotherapeutics, and in particular to a compound as represented by general formula I, a racemate, an R-isomer, an S-isomer and a pharmaceutically acceptable salt thereof and a mixture of same, a preparation method therefor, a pharmaceutical composition containing the compound and the use thereof as an S1P receptor agonist. The oxadiazole compound involved in the present invention can be used for treating S1P receptor agonist related diseases.
Inventors:
LIU HONG (CN)
WANG JIANG (CN)
XIE CEN (CN)
LIU YAMENG (CN)
HU SHULEI (CN)
LI CUINA (CN)
GAO FENG (CN)
WANG KANGLONG (CN)
WANG YONG (CN)
ZHONG XIANCHUN (CN)
SHI YUQIANG (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
WANG JIANG (CN)
XIE CEN (CN)
LIU YAMENG (CN)
HU SHULEI (CN)
LI CUINA (CN)
GAO FENG (CN)
WANG KANGLONG (CN)
WANG YONG (CN)
ZHONG XIANCHUN (CN)
SHI YUQIANG (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
Application Number:
PCT/CN2021/103263
Publication Date:
January 06, 2022
Filing Date:
June 29, 2021
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
C07D413/14; A61K31/4245; A61P3/00; C07D271/06; C07D413/12
Domestic Patent References:
| WO2014055911A1 | 2014-04-10 | |||
| WO2015073140A1 | 2015-05-21 |
Foreign References:
| CN108939074A | 2018-12-07 |
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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