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Title:
OXADIAZOLE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2002/096892
Kind Code:
A1
Abstract:
Oxadiazole derivative represented by the following general formula (I) and nontoxic salts thereof: (I) wherein each symbol is as defined in the description. Because of having a cysteine protease inhibitory activity, the compounds of the formula (I) are useful as preventives and&sol or remedies for inflammatory diseases, diseases caused by apoptosis, diseases caused by abnormal immune response, autoimmune diseases, diseases caused by degradation of bioproteins, shock, circulatory disorders, disorders in the blood coagulation system, malignant tumor, acquired deficiency syndrome (AIDS) and AIDS−related complex, parasitic diseases, neurodegenerative diseases, pulmonary disorders, bone resorption diseases, hypercirinic diseases, etc.

Inventors:
OHMOTO KAZUYUKI (JP)
KAWABATA KAZUHITO (JP)
Application Number:
PCT/JP2002/005251
Publication Date:
December 05, 2002
Filing Date:
May 30, 2002
Export Citation:
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Assignee:
ONO PHARMACEUTICAL CO (JP)
OHMOTO KAZUYUKI (JP)
KAWABATA KAZUHITO (JP)
International Classes:
A61P5/00; A61P7/02; A61P9/00; A61P11/00; A61P19/08; A61P25/28; A61P29/00; A61P31/18; A61P33/00; A61P35/00; A61P37/00; A61P43/00; C07D271/113; C07K5/078; A61K38/00; C07D271/10; (IPC1-7): C07D271/10; A61K31/4245; A61K31/4439; A61K31/454; A61K31/513; A61K31/5377; A61K38/05; A61P5/00; A61P7/02; A61P9/00; A61P11/00; A61P19/08; A61P25/28; A61P29/00; A61P31/18; A61P33/00; A61P35/00; A61P37/00; A61P43/00; C07D413/12; C07K5/06
Domestic Patent References:
WO2001044214A12001-06-21
WO1998049190A21998-11-05
WO1997016433A11997-05-09
Attorney, Agent or Firm:
Ohie, Kunihisa (Horiguchi No.2 Bldg. 7F 2-6, Nihonbashi-Ningyocho, 2-chom, Chuo-ku Tokyo, JP)
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