Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PATCH COMPRISING COLCHICINE AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067722
Kind Code:
A1
Abstract:
Provided are a patch comprising colchicine and a preparation method therefor and use thereof, wherein the patch comprises a polymer matrix layer. The polymer matrix layer comprises the following components in percentage by weight: 0.1%-5.0% of colchicine, 0.005%-15% of a penetration enhancer, and 80%-99% of a pressure-sensitive adhesive. The described patch comprising colchicine can achieve transdermal penetration of an amount sufficient for achieving treatment effect and features no local irritation during pasting and after pasting, no gastrointestinal side effects, and high patient compliance.

Inventors:
XIE WENWEI (CN)
LU SONG (CN)
SUN LINA (CN)
WANG YUAN (CN)
Application Number:
PCT/CN2023/122148
Publication Date:
April 04, 2024
Filing Date:
September 27, 2023
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
DEMOTECH INC (CN)
International Classes:
A61K31/165; A61K9/70; A61P19/06
Domestic Patent References:
WO2021070066A12021-04-15
Foreign References:
CN1165652A1997-11-26
CN101062022A2007-10-31
CN108057018A2018-05-22
Other References:
YARAN LEI: "Formulation and Evaluation of a Drug-in-Adhesive Patch for Transdermal Delivery of Colchicine", PHARMACEUTICS, vol. 14, no. 10, CH , pages 1 - 16, XP093151983, ISSN: 1999-4923, DOI: 10.3390/pharmaceutics14102245
SAN-KONG SONG: "Preparation and quality evaluation of two types of colchicine ethosome patches", vol. 44, no. 17, 30 September 2013 (2013-09-30), pages 2380 - 2385, XP093152006, DOI: 10.7501/j.issn.0253-2670.2013.17.008
Attorney, Agent or Firm:
CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)
Download PDF: