Title:
PENTACYCLIC TRITERPENOID GLYCOSIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/007765
Kind Code:
A1
Abstract:
The present invention provides a pentacyclic triterpenoid glycoside compound, and a preparation method therefor and a use thereof. Specifically, the present invention provides a compound as shown in formula I. The definition of each group is described in the description. The compound can be used for preparing a medicament for treating metabolic diseases such as diabetes and viral diseases caused by influenza virus, coronavirus and the like.
Inventors:
LIU HONG (CN)
WANG JIANG (CN)
LIU YICHU (CN)
YU CHANGYUE (CN)
WANG YIBING (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
WANG JIANG (CN)
LIU YICHU (CN)
YU CHANGYUE (CN)
WANG YIBING (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
Application Number:
PCT/CN2021/104599
Publication Date:
January 13, 2022
Filing Date:
July 05, 2021
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
A61K31/58; C07J63/00; A61P1/16; A61P3/00; A61P3/04; A61P31/16
Domestic Patent References:
| WO2017106836A1 | 2017-06-22 |
Foreign References:
| CN105566435A | 2016-05-11 | |||
| CN104910239A | 2015-09-16 | |||
| CN1853637A | 2006-11-01 | |||
| CN101817862A | 2010-09-01 | |||
| CN108530508A | 2018-09-14 | |||
| CN109481684A | 2019-03-19 |
Other References:
MIQUEL NICOLAS, G DOISNEAU, JM BEAU: "Reductive Samariation of Anomeric 2-Pyridyl Sulfones with Catalytic Nickel: An Unexpected Improvement in the Synthesis of 1, 2-Trans-Diequatorial C-Glycosyl Compounds", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, ¬VERLAG CHEMIE| :, vol. 39, no. 22, 14 November 2000 (2000-11-14), XP055886588, ISSN: 1433-7851, DOI: 10.1002/1521-3773(20001117)39:22<4111::aid-anie4111>3.0.co;2-c
XIANG L; ZHANG L; CHEN X; XIA X; LI R; ZHONG J: "Ursane-type triterpenoid saponins from Elsholtzia bodinieri", NATURAL PRODUCT RESEARCH, TAYLOR & FRANCIS, LONDON, 1 March 2019 (2019-03-01), London , pages 1349 - 1356, XP018535286, ISSN: 1478-6427
XIANG L; ZHANG L; CHEN X; XIA X; LI R; ZHONG J: "Ursane-type triterpenoid saponins from Elsholtzia bodinieri", NATURAL PRODUCT RESEARCH, TAYLOR & FRANCIS, LONDON, 1 March 2019 (2019-03-01), London , pages 1349 - 1356, XP018535286, ISSN: 1478-6427
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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