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Title:
PEPTIDE FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO/2021/062389
Kind Code:
A3
Abstract:
A peptide is disclosed that has an amino acid sequence selected from X1-X2-X3-Gln-Leu-Met- Leu-Cys-Val-Leu-X4-X5-X6 (SEQ ID NO: 3), X1-X2-X3-Gln-X7-Met-X10-Cys-Val-X11-X4-X5- X6 (SEQ ID NO: 4), Ile-Ser-Phe-Gln-Leu-Met-Leu (SEQ ID NO: 5), Leu-Cys-Val-Leu-Asp- Tyr-Phe (SEQ ID NO: 6), X1-X2-X3-Gln-Leu-X8-Leu-X9-Val-Leu-X4-X5-X6 (SEQ ID NO: 7), X1-X2-X3-Gln-Leu-X8-Leu-X9-Val-Leu-X4-X5-X6 (SEQ ID NO: 7), X1-X2-X3-X12-Leu-Met- Leu-Cys-X13-Leu-X4-X5-X6 (SEQ ID NO: 10), Gln-X7-Met-X10-Cys-Val-X11 (SEQ ID NO: 11), Gln-Leu-X8-Leu-X9-Val-Leu (SEQ ID NO: 12), X12-Leu-Met-Leu-Cys-X13-Leu (SEQ ID NO: 13), Asp-Leu-Val-Ile-Ser-Phe-Gln-Leu-Met-Leu-Cys-Val-Leu-Asp-Tyr-Phe-Ile-Lys (SEQ ID NO: 14) and retro-inverso peptides thereof. The peptides disclosed herein may be used to treat liver cancer, lung cancer, breast cancer, pancreatic cancer, or brain cancer.

Inventors:
BORYSOV SERGIY I (US)
Application Number:
PCT/US2020/053128
Publication Date:
May 06, 2021
Filing Date:
September 28, 2020
Export Citation:
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Assignee:
SAINT LEO UNIV (US)
International Classes:
A61P31/12; A61K38/00; A61K39/00; A61P31/14; A61P43/00
Domestic Patent References:
WO1998037091A21998-08-27
Other References:
HOSTA-RIGAU ET AL.: "Multifunctionalized Gold Nanoparticles with Peptides Targeted to Gastrin- Releasing Peptide Receptor of a Tumor Cell Line", BIOCONJUGATE CHEMISTRY, vol. 21, no. 6, 18 May 2010 (2010-05-18), pages 1070 - 1078, XP055180472, DOI: 10.1021/bc1000164
Attorney, Agent or Firm:
HARDING, Ryan L. et al. (US)
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