Title:
PHARMACEUTICAL COMPOSITION FOR IMPROVING OR TREATING POST-SURGICAL HYPOPARATHYROIDISM AND TREATMENT METHOD USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2021/029517
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for improving or treating hypoparathyroidism caused by damage to parathyroid tissue and vascular tissue around the parathyroid gland due to surgery around the neck, and a method for treating post-surgical hypoparathyroidism using the same, and the composition can promote secretion of parathyroid hormone by containing a calcium-sensing receptor antagonist as an active ingredient to help the restoration of damaged parathyroid tissue through neovascularization and angiogenesis, and furthermore, can alleviate hypocalcemia, hyperphosphatemia, and hypercalciuria by increasing the concentration of blood parathyroid hormone to a normal range level. Administration of the composition can improve the quality of life of patients with hypoparathyroidism.
Inventors:
CHOI HAN SEOK (KR)
LIM YUN SUNG (KR)
KIM KWANG JOON (KR)
LIM YUN SUNG (KR)
KIM KWANG JOON (KR)
Application Number:
PCT/KR2020/006293
Publication Date:
February 18, 2021
Filing Date:
May 13, 2020
Export Citation:
Assignee:
UNIV DONGGUK IND ACAD COOP (KR)
International Classes:
A61K31/517; A61K9/00; A61P5/18
Domestic Patent References:
| WO2008107390A1 | 2008-09-12 | |||
| WO2004056365A2 | 2004-07-08 | |||
| WO2004041755A2 | 2004-05-21 |
Foreign References:
| US6417215B1 | 2002-07-09 | |||
| US20050032850A1 | 2005-02-10 |
Attorney, Agent or Firm:
PCR INTELLECTUAL PROPERTY LAW FIRM (KR)
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