Title:
PHARMACEUTICAL COMPOSITION OF PIPERACILLIN SODIUM AND SULBACTAM SODIUM
Document Type and Number:
WIPO Patent Application WO/2017/117882
Kind Code:
A1
Abstract:
Disclosed is a pharmaceutical composition of piperacillin sodium and sulbactam sodium, comprising 2-4 parts by weight of piperacillin sodium and 1 part by weight of sulbactam sodium having a specific rotation of +230° to +235°. By optimizing the process for preparing sulbactam sodium, sulbactam sodium with the specific rotation of +230° to +235° is prepared, and the process for preparing piperacillin sodium is optimized, wherein same is beneficial for improving the stability of the pharmaceutical composition and the use thereof is safer.
Inventors:
YU LEI (CN)
LI CHUANJIANG (CN)
LI JIACHENG (CN)
LI CHUANJIANG (CN)
LI JIACHENG (CN)
Application Number:
PCT/CN2016/078923
Publication Date:
July 13, 2017
Filing Date:
April 11, 2016
Export Citation:
Assignee:
SICHUAN PHARMACEUTICAL IN (CN)
SICHUAN XINGZHI ZHIHUI INTELLECTUAL PROPERTY OPERATION CO LTD (CN)
SICHUAN XINGZHI ZHIHUI INTELLECTUAL PROPERTY OPERATION CO LTD (CN)
International Classes:
A61K31/496; C07D499/86; A61P31/04
Foreign References:
| CN101890014A | 2010-11-24 | |||
| CN103012429A | 2013-04-03 | |||
| CN101322702A | 2008-12-17 | |||
| CN101062032A | 2007-10-31 |
Attorney, Agent or Firm:
CHENGDU XINGZHI PATENT AGENCY(ORDINARY PARTNERSHIP) (CN)
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