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Title:
PHARMACEUTICAL COMPOSITION FOR TREATING FIBROSIS
Document Type and Number:
WIPO Patent Application WO/2020/067333
Kind Code:
A1
Abstract:
To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts without injuring alveolar epithelial cells and thus inhibits lung fibrosis. A pharmaceutical composition for treating fibrosis that comprises a compound represented by formula (I) or (II), a pharmaceutically acceptable salt thereof, or a solvate of the same. [In formula (I): R1 represents an optionally halogenated C1-4 alkyl group; and l represents an integer of 3-6. In formula (II): n represents an integer of 8-12.]

Inventors:
MIZUSHIMA TOHRU (JP)
TANAKA KEN-ICHIRO (JP)
Application Number:
PCT/JP2019/037947
Publication Date:
April 02, 2020
Filing Date:
September 26, 2019
Export Citation:
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Assignee:
LTT BIO PHARMA CO LTD (JP)
MUSASHINO UNIV (JP)
International Classes:
A61K31/4453; A61K31/122; A61K31/397; A61K31/40; A61K31/55; A61P1/16; A61P9/00; A61P11/00; A61P13/12; A61P17/00; C07C50/28; C07D211/14
Domestic Patent References:
WO2009038771A22009-03-26
Foreign References:
JPS58177934A1983-10-18
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See also references of EP 3858351A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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