Title:
PHARMACEUTICAL COMPOSITIONS FOR TREATING DEGENERATIVE NEUROLOGICAL DISEASE WITH MITOCELLS
Document Type and Number:
WIPO Patent Application WO/2016/037587
Kind Code:
A1
Abstract:
MitoCells treated with angelica extract is provided. Also provided is a pharmaceutical composition comprising the MitoCells. The pharmaceutical composition can significantly achieve the goal for treating degenerative neurological disease.
Inventors:
LIN SHINN-ZONG (CN)
HARN HORNG-JYH (CN)
LIU SHIH-PING (CN)
CHENG HAN-CHUNG (CN)
TU CHI-TANG (CN)
HARN HORNG-JYH (CN)
LIU SHIH-PING (CN)
CHENG HAN-CHUNG (CN)
TU CHI-TANG (CN)
Application Number:
PCT/CN2015/089402
Publication Date:
March 17, 2016
Filing Date:
September 11, 2015
Export Citation:
Assignee:
TAIWAN MITOCHONDRION APPLIED TECHNOLOGY CO LTD (CN)
International Classes:
A61K35/12; C12N5/0775; A61K36/232; A61P25/16; C12N5/07; C12N5/0789; C12N5/0797
Domestic Patent References:
| WO2010110755A1 | 2010-09-30 |
Foreign References:
| CN103864947A | 2014-06-18 |
Other References:
SHIH-PING LIU ET AL.: "n-Butylidenephthalide (BP) Maintains Stem Cell Pluripotency by Activating Jak2/Stat3 Pathway and Increases the Efficiency of iPS Cells Generation", PLOS ONE, vol. 7, no. Issue 9, 30 September 2012 (2012-09-30), pages 1 - 12, ISSN: 1932-6203
QIAOZHI WANG ET AL.: "Differentiation of human adipose-derived stem cells into neuron-like cells by Radix Angelicae Sinensis", NEURAL REGENERATION RESEARCH, vol. 8, no. Issue 35, 31 December 2013 (2013-12-31), pages 3353 - 3358, ISSN: 1673-5374
WANG QIAO-ZHI ET AL.: "Studies on human adipose-derived stem cells differentiate into neuro- like cells induced with Chinese Angelica and butylated hydroxyanisol", CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS, vol. 30, no. Issue 1, 31 January 2010 (2010-01-31), pages 99 - 102, ISSN: 0254-1793
QIAOZHI WANG ET AL.: "Differentiation of human adipose-derived stem cells into neuron-like cells by Radix Angelicae Sinensis", NEURAL REGENERATION RESEARCH, vol. 8, no. Issue 35, 31 December 2013 (2013-12-31), pages 3353 - 3358, ISSN: 1673-5374
WANG QIAO-ZHI ET AL.: "Studies on human adipose-derived stem cells differentiate into neuro- like cells induced with Chinese Angelica and butylated hydroxyanisol", CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS, vol. 30, no. Issue 1, 31 January 2010 (2010-01-31), pages 99 - 102, ISSN: 0254-1793
Attorney, Agent or Firm:
BEIJING YUANBEN INTELLECTUAL PROPERTY LAW OFFICE (No.12 Huayuan Road, Haidian District, Beijing 8, CN)
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