Title:
PHENYLETHANOLAMINE DERIVATIVES AS BETA-2 AGONISTS
Document Type and Number:
WIPO Patent Application WO2005090287
Kind Code:
A3
Abstract:
The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
Inventors:
BROWN ALAN DANIEL (GB)
BUNNAGE MARK EDWARD (GB)
GLOSSOP PAUL ALAN (GB)
JAMES KIM (GB)
LANE CHARLOTTE ALICE LOUISE (GB)
LEWTHWAITE RUSSELL ANDREW (GB)
LUNN GRAHAM (GB)
PRICE DAVID ANTHONY (GB)
BUNNAGE MARK EDWARD (GB)
GLOSSOP PAUL ALAN (GB)
JAMES KIM (GB)
LANE CHARLOTTE ALICE LOUISE (GB)
LEWTHWAITE RUSSELL ANDREW (GB)
LUNN GRAHAM (GB)
PRICE DAVID ANTHONY (GB)
Application Number:
PCT/IB2005/000640
Publication Date:
February 16, 2006
Filing Date:
March 10, 2005
Export Citation:
Assignee:
PFIZER LTD (GB)
PFIZER (US)
BROWN ALAN DANIEL (GB)
BUNNAGE MARK EDWARD (GB)
GLOSSOP PAUL ALAN (GB)
JAMES KIM (GB)
LANE CHARLOTTE ALICE LOUISE (GB)
LEWTHWAITE RUSSELL ANDREW (GB)
LUNN GRAHAM (GB)
PRICE DAVID ANTHONY (GB)
PFIZER (US)
BROWN ALAN DANIEL (GB)
BUNNAGE MARK EDWARD (GB)
GLOSSOP PAUL ALAN (GB)
JAMES KIM (GB)
LANE CHARLOTTE ALICE LOUISE (GB)
LEWTHWAITE RUSSELL ANDREW (GB)
LUNN GRAHAM (GB)
PRICE DAVID ANTHONY (GB)
International Classes:
A61K31/165; A61K31/472; C07C237/20; C07D217/06; (IPC1-7): C07C237/20; A61K31/165; A61K31/472; C07D217/06
Domestic Patent References:
| WO2003042160A1 | 2003-05-22 | |||
| WO2001042193A1 | 2001-06-14 | |||
| WO2003091204A1 | 2003-11-06 |
Foreign References:
| EP0006735A1 | 1980-01-09 | |||
| EP0236624A2 | 1987-09-16 | |||
| FR2562889A1 | 1985-10-18 | |||
| FR2319334A1 | 1977-02-25 | |||
| EP1477167A1 | 2004-11-17 |
Other References:
APPERLEY G H ET AL: "Selectivity of Beta-adrenoceptor agonists and antagonists on bronchial, skeletal, vascular and cardiac muscle in the anaesthetized cat", BRITISH JOURNAL OF PHARMACOLOGY, BASINGSTOKE, HANTS, GB, vol. 57, no. 2, 1976, pages 235 - 246, XP000926140, ISSN: 0007-1188
BONNERT R V ET AL: "DUAL D2-RECEPTOR AND BETA2-ADRENOCEPTOR AGONISTS FOR THE TREATMENT OF AIRWAY DISEASES. 1. DISCOVERY AND BIOLOGICAL EVALUATION OF SOME 7-(2-AMINOETHYL)- 4-HYDROXYBENZOTHIAZOL-2(3H)-ONE ANALOGUES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 41, no. 25, 1998, pages 4915 - 4917, XP000978960, ISSN: 0022-2623
CAMPILLO N ET AL: "NOVEL BRONCHODILATORS IN THE TREATMENT OF ASTHMA AND COPD", EXPERT OPINION ON THERAPEUTIC PATENTS, ASHLEY PUBLICATIONS, GB, vol. 1, no. 12, 2002, pages 53 - 63, XP008002080, ISSN: 1354-3776
BONNERT R V ET AL: "DUAL D2-RECEPTOR AND BETA2-ADRENOCEPTOR AGONISTS FOR THE TREATMENT OF AIRWAY DISEASES. 1. DISCOVERY AND BIOLOGICAL EVALUATION OF SOME 7-(2-AMINOETHYL)- 4-HYDROXYBENZOTHIAZOL-2(3H)-ONE ANALOGUES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 41, no. 25, 1998, pages 4915 - 4917, XP000978960, ISSN: 0022-2623
CAMPILLO N ET AL: "NOVEL BRONCHODILATORS IN THE TREATMENT OF ASTHMA AND COPD", EXPERT OPINION ON THERAPEUTIC PATENTS, ASHLEY PUBLICATIONS, GB, vol. 1, no. 12, 2002, pages 53 - 63, XP008002080, ISSN: 1354-3776
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