Title:
PHOSPHORAMIDATE COMPOUND AND PREPARATION METHOD AND CRYSTAL THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/045581
Kind Code:
A1
Abstract:
The present invention involves a composition rich in compound 61501b, wherein the compound 61501b has a purity not less than 90% or more. The composition has a significant advantage in preparing high-purity compound Sp-1. In addition, the present invention also provides a preparation method of composition rich in compound 61501b. The method adopts a crystallization technique to perform separation and purification, has a simple and convenient operation and good reproducibility, and therefore the compound 61501b in the prepared composition has high purity and quality. Further, the present invention also involves a novel crystal of compound 61501b.
Inventors:
YUAN JIANDONG (CN)
HUANG YANGQING (CN)
MIAO LINFENG (CN)
GU JIANING (CN)
LIANG CHAOHUA (CN)
WANG ZHENGYE (CN)
SUN ZHANLI (CN)
HUANG YANGQING (CN)
MIAO LINFENG (CN)
GU JIANING (CN)
LIANG CHAOHUA (CN)
WANG ZHENGYE (CN)
SUN ZHANLI (CN)
Application Number:
PCT/CN2016/098845
Publication Date:
March 23, 2017
Filing Date:
September 13, 2016
Export Citation:
Assignee:
BRIGHTGENE BIO-MEDICAL TECH CO LTD (CN)
International Classes:
C07H19/10; C07H19/06; C07H19/073; C07H19/16
Domestic Patent References:
| WO2012075140A1 | 2012-06-07 | |||
| WO2016055769A1 | 2016-04-14 | |||
| WO2005012327A2 | 2005-02-10 | |||
| WO2015198058A1 | 2015-12-30 |
Foreign References:
| CN104640444A | 2015-05-20 |
Other References:
See also references of EP 3351550A4
Attorney, Agent or Firm:
SUNSHINE INTELLECTUAL PROPERTY INTERNATIONAL CO., LTD (CN)
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