Title:
PHOTORESPONSIVE NUCLEOTIDE ANALOG CAPABLE OF PHOTOCROSSLINKING IN VISIBLE LIGHT REGION
Document Type and Number:
WIPO Patent Application WO/2019/022158
Kind Code:
A1
Abstract:
Provided are a compound represented by formula I that can be used in nucleic acid photoreaction techniques, and a photoreactive crosslinking agent comprising the compound.
Inventors:
FUJIMOTO KENZO (JP)
NAKAMURA SHIGETAKA (JP)
NAKAMURA SHIGETAKA (JP)
Application Number:
PCT/JP2018/027961
Publication Date:
January 31, 2019
Filing Date:
July 25, 2018
Export Citation:
Assignee:
JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECH (JP)
International Classes:
C07D491/052; C07H19/24; C07H21/04; C12N15/09
Domestic Patent References:
| WO2009066447A1 | 2009-05-28 |
Foreign References:
| JP2001348398A | 2001-12-18 | |||
| JPH04506206A | 1992-10-29 | |||
| JP3753938B2 | 2006-03-08 | |||
| JP3753942B2 | 2006-03-08 | |||
| JPS4814904B1 | 1973-05-10 | |||
| JPS4940311B1 | 1974-11-01 |
Other References:
VRONTELI, A. ET AL.: "Synthesis of fused pyranocarbazolones with biological interest", ARKIVOC, vol. 2015, no. 3, 25 February 2015 (2015-02-25), pages 111 - 123, XP055572471, ISSN: 1551-7012
RODIGHIERO, P. ET AL.: "Pyrrolocoumarin derivatives as potential photoreagents toward DNA", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 24, no. 4, August 1987 (1987-08-01), pages 1041 - 1043, XP055572482, ISSN: 0022-152X
YOSHIMURA, Y. ET AL.: "Ultrafast reversible photo- cross-linking reaction: Toward in situ DNA manipulation", ORGANIC LETTERS, vol. 10, no. 15, 27 June 2008 (2008-06-27), pages 3227 - 3230, XP008134569, ISSN: 1523-7060
FUJIMOTO, K. ET AL.: "DNA photo-cross-linking using pyranocarbazole and visible light", ORGANIC LETTERS, vol. 20, no. 10, 27 April 2018 (2018-04-27), pages 2802 - 2805, XP055572495, ISSN: 1523-7052
J. PHOTOPOLY. S. TECH., vol. 27, 2014, pages 485
See also references of EP 3660022A4
RODIGHIERO, P. ET AL.: "Pyrrolocoumarin derivatives as potential photoreagents toward DNA", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 24, no. 4, August 1987 (1987-08-01), pages 1041 - 1043, XP055572482, ISSN: 0022-152X
YOSHIMURA, Y. ET AL.: "Ultrafast reversible photo- cross-linking reaction: Toward in situ DNA manipulation", ORGANIC LETTERS, vol. 10, no. 15, 27 June 2008 (2008-06-27), pages 3227 - 3230, XP008134569, ISSN: 1523-7060
FUJIMOTO, K. ET AL.: "DNA photo-cross-linking using pyranocarbazole and visible light", ORGANIC LETTERS, vol. 20, no. 10, 27 April 2018 (2018-04-27), pages 2802 - 2805, XP055572495, ISSN: 1523-7052
J. PHOTOPOLY. S. TECH., vol. 27, 2014, pages 485
See also references of EP 3660022A4
Attorney, Agent or Firm:
AXIS PATENT INTERNATIONAL et al. (JP)
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