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Patent Searching and Data


Title:
PHYSIOLOGICALLY ACTIVE SUBSTANCE CARRIER
Document Type and Number:
WIPO Patent Application WO/2018/143787
Kind Code:
A1
Abstract:
The present invention relates to a physiologically active substance carrier, comprising: a physiologically active substance; and porous silica particles supporting the physiologically active substance and having a plurality of pores with a diameter of 5-100 nm, wherein the porous silica particles have particular physical properties, can deliver all various drugs by a supported amount in a sustained manner, and can be parenterally administered.

Inventors:
WON CHEOL HEE (KR)
Application Number:
PCT/KR2018/001617
Publication Date:
August 09, 2018
Filing Date:
February 06, 2018
Export Citation:
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Assignee:
LEMONEX INC (KR)
International Classes:
A61K9/00; A61K9/14; A61K9/16; C01B33/12
Foreign References:
KR20160011565A2016-02-01
US20100104650A12010-04-29
KR20100117433A2010-11-03
EP0270799A11988-06-15
EP0268110A11988-05-25
US4766106A1988-08-23
US4179337A1979-12-18
US4495285A1985-01-22
US4609546A1986-09-02
Other References:
CROISSANT, J. G. ET AL.: "Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles", ADVANCED MATERIALS, vol. 29, no. 9, 13 January 2017 (2017-01-13), pages 1 - 51, XP055532645
YAMADA, H. ET AL.: "Preparation of Colloidal Mesoporous Silica Nanoparticles with Different Diameters and Their Unique Degradation Behavior in Static Aqueous Systems", CHEMISTRY OF MATERIALS, vol. 24, 2012, pages 1462 - 1471, XP055532669
HE, Q. ET AL.: "The Three-stage in Vitro Degradation Behavior of Mesoporous Silica in Simulated Body Fluid", MICROPOROUS AND MESOPOROUS MATERIALS, vol. 131, 2010, pages 314 - 320, XP026940848
HUANG, X. ET AL.: "Characterization and Comparison of Mesoporous Silica Particles for Optimized Drug Delivery", NANOMATERIALS AND NANOTECHNOLOGY, vol. 4, no. 2, 2014, pages 1 - 15, XP055532688
"Remington: The Science and Practice of Pharmacy", 2000, U.S.P., REMINGTON, MACK PUBLISHING COMPANY
KNAUF ET AL., J. BIO. CHEM., vol. 263, 1988, pages 15064 - 15070
Attorney, Agent or Firm:
DOOHO IP LAW FIRM (KR)
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