Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PIPERAZINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2006/062110
Kind Code:
A1
Abstract:
A compound represented by the formula (I): [wherein R1 represents C3-9 branched alkyl; R2 represents, e.g., linear or branched, C2-9 alkyl optionally substituted by halogen, etc.; and X represents oxygen, etc.] (provided that the following cases are excluded: the case where R1 is tert-butyl, R2 is 2-methylpropyl, phenyl, tert-butyl, benzyl, or cyclohexyl, and X is oxygen and the case where R1 is tert-butyl, R2 is adamantly, neopentyl, or cyclohexylethenyl, and R3 is a single bond); or a pharmaceutically acceptable salt of the compound. The compound and salt have inhibitory activity against metabotropic glutamate receptor 1. They are hence useful for the treatment of diseases such as convulsion, acute pain, inflammatory pain, chronic pain, psychofunctional disorders including schizophrenia, and anxiety.

More Like This:
WO/2011/058932N-BENZYL AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
WO/1983/0019501-PIPERAZINOCARBOXYLATES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Inventors:
SATOH ATSUSHI (JP)
NAGATOMI YASUSHI (JP)
KIMURA TOSHIFUMI (JP)
SUZUKI GENTAROH (JP)
SATO AKIO (JP)
OHTA HISASHI (JP)
Application Number:
PCT/JP2005/022408
Publication Date:
June 15, 2006
Filing Date:
November 30, 2005
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
BANYU PHARMA CO LTD (JP)
SATOH ATSUSHI (JP)
NAGATOMI YASUSHI (JP)
KIMURA TOSHIFUMI (JP)
SUZUKI GENTAROH (JP)
SATO AKIO (JP)
OHTA HISASHI (JP)
International Classes:
C07D295/20; A61K31/495; A61K31/496; A61P9/10; A61P25/00; A61P25/04; A61P25/08; A61P25/16; A61P25/22; A61P39/02; C07D309/06; C07D319/06
Domestic Patent References:
WO2003018538A12003-03-06
WO1997018203A11997-05-22
Foreign References:
JP2002518478A2002-06-25
JP2002507992A2002-03-12
JP2000505795A2000-05-16
JP2004511544A2004-04-15
JP2004519438A2004-07-02
JPH02262654A1990-10-25
FR1575589A1969-07-25
Attorney, Agent or Firm:
BANYU PHARMACEUTICAL CO., LTD. (1-13-12 Kudankita, Chiyoda-k, Tokyo ., JP)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: OPTICAL COMPENSATORY ELEMENT AND METHOD FOR MANUFACTURING THEREOF, WAVE PLATE AND METHOD FOR MANUFAC...

Next Patent: INFORMATION TRANSMISSION THROUGH-HUMAN-BODY SYSTEM AND TRANSMITTER/RECEIVER