Title:
PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/166845
Kind Code:
A1
Abstract:
The present invention relates to a compound of formula (I) capable of inhibiting plasmin activity and having blood coagulation and hemostasis activity, and a pharmaceutically acceptable salt, hydrate, isomer, prodrug, and mixture thereof, wherein R1 to R3 are as defined in the description.
Inventors:
YANG ANLE (CN)
JI SEN (CN)
WANG ZHI (CN)
WANG HAO (CN)
ZHANG DEWEI (CN)
WANG XIAO (CN)
SHEN HUAN (CN)
XIANG JIE (CN)
XIAN JIALING (CN)
WANG YAN (CN)
HU XIAO (CN)
ZHANG XIAODONG (CN)
TANG JUN (CN)
JI SEN (CN)
WANG ZHI (CN)
WANG HAO (CN)
ZHANG DEWEI (CN)
WANG XIAO (CN)
SHEN HUAN (CN)
XIANG JIE (CN)
XIAN JIALING (CN)
WANG YAN (CN)
HU XIAO (CN)
ZHANG XIAODONG (CN)
TANG JUN (CN)
Application Number:
PCT/CN2022/074754
Publication Date:
August 11, 2022
Filing Date:
January 28, 2022
Export Citation:
Assignee:
SCINNOHUB PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D491/12; A61K31/4375; A61P7/04; C07D471/04
Domestic Patent References:
| WO2008149163A2 | 2008-12-11 | |||
| WO2015067549A1 | 2015-05-14 | |||
| WO2012047156A1 | 2012-04-12 |
Foreign References:
| CN107108638A | 2017-08-29 | |||
| CN102459246A | 2012-05-16 |
Other References:
TENGBORN LBLOMBACK MBERNTORP E, THROMB RES, vol. 135, no. 2, February 2015 (2015-02-01), pages 231 - 42
NG WJERATH AWQSOWICZ M, ANAESTHESIOL INTENSIVE THER, vol. 47, no. 4, 2015, pages 339 - 50
NG WJERATH AWQSOWICZ M, ANAESTHESIOL INTENSIVE THER, vol. 47, no. 4, 2015, pages 339 - 50
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
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