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Title:
POROUS SPUN POLYMERIC STRUCTURES AND METHOD OF MAKING SAME
Document Type and Number:
WIPO Patent Application WO2004061177
Kind Code:
A3
Abstract:
A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 p,m to about 250 gm, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.

Inventors:
DAO KINH-LUAN LENNY D
CHIN YEM
ZHONG SHENG-PING
MOHAN KSHITIJ
VU LIEM
Application Number:
PCT/US2003/041578
Publication Date:
November 25, 2004
Filing Date:
December 30, 2003
Export Citation:
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Assignee:
SCIMED LIFE SYSTEMS INC (US)
International Classes:
B01D39/16; A61M1/36; (IPC1-7): B29C67/00; A61M1/36; B01D39/16
Domestic Patent References:
WO2001087575A22001-11-22
Foreign References:
US5121329A1992-06-09
US6176874B12001-01-23
US20020113331A12002-08-22
US5402351A1995-03-28
FR2821762A12002-09-13
US4475972A1984-10-09
US6146567A2000-11-14
US6056993A2000-05-02
US3836416A1974-09-17
US5936861A1999-08-10
Other References:
DIETMAR W. HUTMACHER: "Scaffolds in tissue engineering bone and cartilage", BIOMATERIALS, vol. 21, 15 December 2000 (2000-12-15), pages 2529 - 2543, XP002289347
IWAN ZEIN ET AL.: "Fused deposition modeling of novel scaffold architectures for tissue engineering applications", BIOMATERIALS, vol. 23, 15 February 2002 (2002-02-15), pages 1169 - 1185, XP002289348
PATENT ABSTRACTS OF JAPAN vol. 0154, no. 21 (C - 0878) 25 October 1991 (1991-10-25)
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