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Patent Searching and Data


Title:
PROBIOTIC MICROCAPSULE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/160540
Kind Code:
A1
Abstract:
A probiotic microcapsule and a preparation method therefor, relating to the technical field of probiotic products. The method comprises the following steps: (a) preparation of a probiotic-loaded capsule core: mixing capsule core materials comprising probiotic powder, microcrystalline cellulose and starch, then adding a hydroxypropyl methyl cellulose solution and mixing well; and preparing the obtained mixed material into a spherical particle capsule core by using an extrusion-spheronization method; and (b) atomization-based coating: forming a single-layer or multilayer coating on the capsule core by using a coating material solution by means of atomization, to obtain a core-shell microcapsule. The prepared probiotic microcapsule is large in loading capacity, uniform in microcapsule particles, and controllable in particle size; moreover, the probiotic microcapsule is tolerant to storage, targeted to intestinal tracts and resistant to gastric acid, and has high temperature stability.

Inventors:
YAO, Mingfei (CN)
HAN, Shengyi (CN)
JIN, Xin (CN)
HUANG, Weixin (CN)
XIE, Jiaojiao (CN)
LU, Yanmeng (CN)
WANG, Bona (CN)
GAO, Ling (CN)
YU, Chihui (CN)
LI, Lanjuan (CN)
Application Number:
PCT/CN2021/097408
Publication Date:
August 04, 2022
Filing Date:
May 31, 2021
Export Citation:
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Assignee:
SHAOXING TONGCHUANG BIOTECHNOLOGY CO., LTD (CN)
International Classes:
A23L33/135; A23L29/30; A23P10/30; A23P20/18
Attorney, Agent or Firm:
BEIJING KEYI INTELLECTUAL PROPERTY FIRM (CN)
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