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Title:
PROBIOTICS FOR INHIBITING AND PREVENTING PROGRESSION OF RENAL DISEASES, AND COMPOSITIONS FOR INHIBITING AND PREVENTING PROGRESSION OF RENAL DISEASES COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2019/117654
Kind Code:
A1
Abstract:
The present invention provides probiotics for inhibiting and preventing the progression of renal diseases and a composition for inhibiting and preventing the progression of renal diseases comprising the same; and to novel a Lactobacillus acidophilus BP105 strain, a Lactobacillus salivarius BP121 strain, and a composition for inhibiting and preventing the progression of renal diseases comprising the same. The novel probiotics, the Lactobacillus acidophilus BP105 strain and the Lactobacillus salivarius BP121 strain, exhibit excellent indoxyl sulfate removal ability, paracresol removal ability, and phosphorus absorption ability.

Inventors:
KIM SU AE (KR)
OH CHANG TAEK (KR)
LEE JONG HUN (KR)
LIM SU HWAN (KR)
KIM JEOM YONG (KR)
PARK SUN KYU (KR)
JANG MIN JUNG (KR)
LIM MIN JU (KR)
Application Number:
PCT/KR2018/015883
Publication Date:
June 20, 2019
Filing Date:
December 13, 2018
Export Citation:
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Assignee:
GREEN CROSS WELLBEING CORP (KR)
International Classes:
A61K35/741; A23L33/135; A61P13/12; C12N1/20; C12R1/225; C12R1/23
Foreign References:
JP2008545428A2008-12-18
KR20140026326A2014-03-05
KR101684289B12016-12-09
Other References:
LIM, IN SEOK ET AL.: "The Effect of Lactic Acid Bacteria Isolates on the Urinary Tract Pathogens to Infants in Vitro", JOURNAL OF KOREAN MEDICAL SCIENCE, vol. 24, no. 1, 2009, pages S57 - S62, XP055618870, DOI: 10.3346/jkms.2009.24.S1.S57
GUIDA, B. ET AL.: "Effect of Short-term Synbiotic Treatment on Plasma P-cresol Levels in Patients with Chronic Renal Failure: A Randomized Clinical Trial", NUTRITION, METABOLISM & CARDIOVASCULAR DISEASES, vol. 24, no. 9, 2014, pages 1043 - 1049, XP029041580, DOI: 10.1016/j.numecd.2014.04.007
KHALIL, ROWAIDA ET AL.: "Evaluation of the Probiotic Potential of Lactic Acid Bacteria Isolated from Faeces of Breast-fed Infants in Egypt", AFRICAN JOURNAL OF BIOTECHNOLOGY, vol. 6, no. 7, 2007, pages 939 - 949, XP002692913
See also references of EP 3741376A4
Attorney, Agent or Firm:
KIM, Sung Ho et al. (KR)
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