A PROCESS FOR THE PREPARATION OF PIROXICAM: B-CYCLODEXTRIN INCLUSION COMPOUNDS

Title:

A PROCESS FOR THE PREPARATION OF PIROXICAM: B-CYCLODEXTRIN INCLUSION COMPOUNDS

Document Type and Number:

WIPO Patent Application WO2003105906

Kind Code:

A8

Abstract:

The present invention relates to a process for the preparation of inclusion compounds of piroxicam with beta-cyclodextrin. More particularly, according to the process of the invention, the aqueous solution of two components is subjected, before drying, to a freezing process at very high rate. The resulting products have physico-chemical characteristics as well as technological and biopharmaceutical properties which are advantageous compared with those obtained according to the prior art processes. The resulting products are suitable for preparing pharmaceutical compositions for the oral administration.

Inventors:

CAPOCCHI ANDREA (IT)

Application Number:

PCT/EP2003/006142

Publication Date:

April 22, 2004

Filing Date:

June 12, 2003

Export Citation:

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Assignee:

CHIESI FARMA SPA (IT)
CAPOCCHI ANDREA (IT)

International Classes:

A61K31/5415; A61K47/48; (IPC1-7): A61K47/48

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