PROCESS FOR PREPARING LACTIC ACID BACTERIA NUCLEOTIDE INCLUDING LOW-MOLECULAR WEIGHT FUNCTIONAL BIOMATERIAL, AND CUBOSOME PREPARED THEREBY

Title:

PROCESS FOR PREPARING LACTIC ACID BACTERIA NUCLEOTIDE INCLUDING LOW-MOLECULAR WEIGHT FUNCTIONAL BIOMATERIAL, AND CUBOSOME PREPARED THEREBY

Document Type and Number:

WIPO Patent Application WO/2020/085720

Kind Code:

A1

Abstract:

The present invention relates to a process for simultaneously preparing a lactic acid bacteria nucleotide and a low-molecular weight functional biomaterial having utility in industries related to skincare and cosmetics, and more specifically, to a process for preparing a lactic acid bacteria nucleotide (cubosome) including a low-molecular weight functional biomaterial, the process capable of addressing two tasks simultaneously via a single cell disruption process (2-in-1 preparation method), one of which is to convert a high-molecular weight functional biomaterial to a low-molecular weight functional biomaterial, and the other of which is to elute a lactic acid bacteria nucleotide component. According to the present invention, the process effectively eliminates cytoplasmic proteins and cell wall components inherent to lactic acid bacteria that affect the skin microbiome and the generation of fermented odors of raw materials, and produces a lactic acid bacteria-derived nucleotide in high concentration whose stability is increased by including an exogenous low-molecular weight biomaterial, wherein the lactic acid bacteria-derived nucleotide thus produced can be effectively used as a biomaterial in the cosmetics, food, and drug industries.

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Inventors:

JEONG HYUN CHEOL (KR)
LEE SEUNG HUN (KR)
YU HEUI JONG (KR)
SOHN JO HANN (KR)

Application Number:

PCT/KR2019/013727

Publication Date:

April 30, 2020

Filing Date:

October 18, 2019

Export Citation:

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Assignee:

SK BIOLAND CO LTD (KR)

International Classes:

C07H19/16; C07K14/78; C07K19/00; C08B37/00

Foreign References:

KR20140135210A	2014-11-25
KR20130115943A	2013-10-22
JP2009526529A	2009-07-23
KR101754218B1	2017-07-06
KR20140002092A	2014-01-07

Attorney, Agent or Firm:

LEE, Moon Sup (KR)

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