PROCESS FOR PRODUCING DIBENZOTHIEPIN DERIVATIVE

Title:

PROCESS FOR PRODUCING DIBENZOTHIEPIN DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/1996/022289

Kind Code:

A1

Abstract:

A useful process for producing 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid which comprises conducting the Friedel-Crafts reaction of 10,11-dihydrodibenzo[b,f]thiepin-10-one with 2-halogenopropionyl halide to yield a ketone derivative, reacting the same with an alcoholate to convert the same into a hydroxy acetal derivative, and subjecting the obtained derivative to a rearrangement reaction.

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Inventors:

YAMAMOTO MASAO (JP)
IKEDA SHIGEO (JP)
TENDO ATSUSI (JP)

Application Number:

PCT/JP1996/000067

Publication Date:

July 25, 1996

Filing Date:

January 18, 1996

Export Citation:

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Assignee:

NIPPON CHEMIPHAR CO (JP)
YAMAMOTO MASAO (JP)
IKEDA SHIGEO (JP)
TENDO ATSUSI (JP)

International Classes:

C07D337/14; (IPC1-7): C07D337/14

Foreign References:

EP0309626A1	1989-04-05
JPS61251682A	1986-11-08

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