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Title:
PROCESS FOR PRODUCING LAMIVUDINE AND EMTRICITABINE
Document Type and Number:
WIPO Patent Application WO/2017/216709
Kind Code:
A3
Abstract:
This invention provides for flow and batch synthesis processes for the production of Lamivudine and Emtricitabine, including flow and batch synthesis processes wherein at least of the synthesis steps are conducted in a solvent free environment.

Inventors:
MANDALA DEVENDER (IN)
WATTS PAUL (ZA)
Application Number:
PCT/IB2017/053481
Publication Date:
February 15, 2018
Filing Date:
June 13, 2017
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Assignee:
UNIV NELSON MANDELA METROPOLITAN (ZA)
International Classes:
C07D411/04
Domestic Patent References:
WO2013021290A12013-02-14
Other References:
MANDALA, DEVENDER ET AL: "Semi-continuous multi-step synthesis of lamivudine", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 15, no. 16, 27 March 2017 (2017-03-27), pages 3444 - 3454, XP002776948, DOI: 10.1039/C7OB00480J
Attorney, Agent or Firm:
SPOOR & FISHER et al. (ZA)
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