THE PROCESS FOR PRODUCING SIMVASTATIN - HUAIBEI HUIKE PHARMACEUTICAL C

Title:

THE PROCESS FOR PRODUCING SIMVASTATIN

Document Type and Number:

WIPO Patent Application WO/2006/034641

Kind Code:

A1

Abstract:

The present invention discloses a process for producing Simvastatin and intermediate thereof. The present invention uses inexpensive and available reagent, its condition is mild, and it leaves out the protective and deprotective steps which are necessary in prior methods. Compared with prior art, the esterifying condition in 8-position is greatly simplified.

Inventors:

YE HONGPING (CN)
SUN MENG (US)
ZHU ZUOLIN (US)

Application Number:

PCT/CN2005/001572

Publication Date:

April 06, 2006

Filing Date:

September 26, 2005

Export Citation:

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Assignee:

HUAIBEI HUIKE PHARMACEUTICAL C (CN)
YE HONGPING (CN)
SUN MENG (US)
ZHU ZUOLIN (US)

International Classes:

C07C59/46; C07D309/06; C07C69/732; C07D309/30; C07D319/06

Foreign References:

CN1290261A	2001-04-04
EP0486153A2	1992-05-20
US5223415A	1993-06-29

Attorney, Agent or Firm:

SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (435 Guiping Road, 3 Shanghai, CN)

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