PRODUCTION OF GLYCOSYLATED MACROLIDES IN E. COLI

Title:

PRODUCTION OF GLYCOSYLATED MACROLIDES IN E. COLI

Document Type and Number:

WIPO Patent Application WO2004024744

Kind Code:

A3

Abstract:

Methods and materials are provided for E. coli host cells containing an expression system for producing NDP 6-deoxy-sugar, which may also comprise an expression system for expressing 6-deoxyglycosyl transferase and/or an expression system for producing a polyketide and/or polyketide oxidation enzymes.

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Inventors:

KHOSLA CHAITAN
GRAMAJO HUGO

Application Number:

PCT/US2003/024109

Publication Date:

July 15, 2004

Filing Date:

July 31, 2003

Export Citation:

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Assignee:

UNIV LELAND STANFORD JUNIOR (US)
KOSAN BIOSCIENCES INC (US)

International Classes:

C07H17/08; C07H21/04; C12N1/21; C12N9/00; C12N9/10; C12N15/52; C12N15/74; C12P19/30; C12P19/62; C12Q1/68; (IPC1-7): C12N1/20; C07H21/04

Foreign References:

US6117659A	2000-09-12
US6265202B1	2001-07-24
US6509455B1	2003-01-21

Other References: