Title:
PRODUCTION METHOD FOR COMPOSITION FOR CELL CULTURING, COMPOSITION FOR CELL CULTURING OBTAINED BY SAME, AND CELL CULTURING METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/066113
Kind Code:
A1
Abstract:
The present invention provides a production method for a composition for cell culturing. This production method comprises: (1) a step for subjecting algae to an acid hydrolysis treatment and/or an alkali hydrolysis treatment; (2) a step for neutralizing the hydrolysis product obtained in the step (1) to obtain an algae extract; and (3) a step for mixing the algae extract with a medium for cell culturing, wherein the medium for cell culturing does not substantially contain L-glutamine.
Inventors:
SHIMIZU TATSUYA (JP)
HARAGUCHI YUJI (JP)
ASAHI TORU (JP)
OKAMOTO YUTA (JP)
HARAGUCHI YUJI (JP)
ASAHI TORU (JP)
OKAMOTO YUTA (JP)
Application Number:
PCT/JP2020/037471
Publication Date:
April 08, 2021
Filing Date:
October 01, 2020
Export Citation:
Assignee:
UNIV TOKYO WOMENS MEDICAL (JP)
International Classes:
C12N5/07; C12N1/00; C12N1/12
Domestic Patent References:
| WO2016208747A1 | 2016-12-29 |
Foreign References:
| JP2010022331A | 2010-02-04 | |||
| JP2014509252A | 2014-04-17 | |||
| JPS5765179A | 1982-04-20 | |||
| JPS57206384A | 1982-12-17 |
Other References:
HARAGUCHI, YUJI, YUKI KAGAWA; KATSUHISA SAKAGUCHI; KATSUHISA MATSUURA; TATSUYA SHIMIZU; TERUO OKANO: "Thicker three-dimensional tissue from a 'symbiotic recycling system' combining mammalian cells and algae", SCIENTIFIC REPORTS, vol. 7, no. 41594, 2017, pages 1 - 10, XP055530164, DOI: 10.1038/srep41594
L. WANGM. MINY. LIP. CHENY. CHEN ET AL.: "Cultivation of green algae Chlorella sp. in different wastewaters from municipal wastewater treatment plant", APPL. BIOCHEM. BIOTECHNOL., vol. 162, 2010, pages 1174 - 1186
F. ROSSIE.J. OLGUINL. DIELSR. DE PHILIPPIS: "Microbial fixation of C02 in water bodies and in drylands to combat climate change, soil loss and desertification", N. BIOTECHNOL., vol. 32, 2015, pages 109 - 120
J. CHENGY. ZHUZ. ZHANGW. YANG: "Modification and improvement of microalgae strains for strengthening C02 fixation from coal-fired flue gas in power plants", BIORESOUR. TECHNOL., 2019
I. AJJAWIJ. VERRUTOM. AQUIL.B. SORIAGAJ. COPPERSMITH ET AL.: "Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator", NAT. BIOTECHNOL., vol. 35, 2017, pages 647 - 652, XP055540971, DOI: 10.1038/nbt.3865
S.H. HOS.W. HUANGC.Y. CHENT. HASUNUMAA. KONDO ET AL.: "Bioethanol production using carbohydrate-rich microalgae biomass as feedstock", BIORESOUR. TECHNOL., vol. 135, 2013, pages 191 - 198, XP028579618, DOI: 10.1016/j.biortech.2012.10.015
G.E. LAKATOSK. RANGLOVAJ. C. MANOELT. GRIVALSKYJ. KOPECKY ET AL.: "Bioethanol production from microalgae polysaccharides", FOLIA MICROBIOL. (PRAHA)., 2019
S. MCCUSKERP.R. BUFFZ. YUA.J FASCETTI: "Amino acid content of selected plant, algae and insect species: a search for alternative protein sources for use in pet foods", J. NUTR. SCI., vol. 3, 2014, pages e39
G. GUTIERREZ-SALMEANL. FABILA-CASTILLOG. CHAMORRO-CEVALLOS: "Nutritional and toxicological aspects of Spirulina (Arthrospira", NUTR. HOSP., vol. 32, 2015, pages 34 - 40
E.T. ALORIO.O. BABALOLA: "Microbial inoculants for improving crop quality and human health in Africa", FRONT. MICROBIOL., vol. 9, 2018, pages 2213
M.I. KHANJ. H. SHINJ. D. KIM: "The promising future of microalgae: current status, challenges and optimization of a sustainable and renewable industry for biofuels, feed and other products", MICROB. CELL FACT., vol. 17, 2018, pages 36
A.K. SINGHM.P. SINGH: "Importance of algae as a potential source of biofuel", CELL MOL. BIOL. (NOISY-LE-GRAND, vol. 60, 2014, pages 106 - 109
Y. HARAGUCHIY. KAGAWAK. SAKAGUCHIK. MATSUURAT. SHIMIZU ET AL.: "Thicker three-dimensional tissue from a ''symbiotic recycling system'' combining mammalian cells and algae", SCI. REP., vol. 7, 2017, pages 41594
Y. HARAGUCHIW. SEKINET. SHIMIZUM. YAMATOS. MIYOSHI, A. ET AL.: "Development of a new assay system for evaluating the permeability of various substances through three-dimensional tissue", TISSUE ENG. PART C METHODS., vol. 16, 2010, pages 685 - 692
Y. HARAGUCHIT. SHIMIZUT. SASAGAWAH. SEKINEK. SAKAGUCHI ET AL.: "Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro", NAT. PROTOC., vol. 7, 2012, pages 850 - 858
E.W. BECKER: "Micro-algae as a source of protein", BIOTECHNOL. ADV., vol. 25, 2007, pages 207 - 210, XP005862318, DOI: 10.1016/j.biotechadv.2006.11.002
P. SPOLAOREC. JOANNIS-CASSANE. DURANA. ISAMBERT: "Commercial applications of microalgae", J. BIOSCI. BIOENG., vol. 101, 2006, pages 87 - 96
L. WANGM. MINY. LIP. CHENY. CHEN ET AL.: "Cultivation of green algae Chlorella sp. in different wastewaters from municipal wastewater treatment plant", APPL. BIOCHEM. BIOTECHNOL., vol. 162, 2010, pages 1174 - 1186
F. ROSSIE.J. OLGUINL. DIELSR. DE PHILIPPIS: "Microbial fixation of C02 in water bodies and in drylands to combat climate change, soil loss and desertification", N. BIOTECHNOL., vol. 32, 2015, pages 109 - 120
J. CHENGY. ZHUZ. ZHANGW. YANG: "Modification and improvement of microalgae strains for strengthening C02 fixation from coal-fired flue gas in power plants", BIORESOUR. TECHNOL., 2019
I. AJJAWIJ. VERRUTOM. AQUIL.B. SORIAGAJ. COPPERSMITH ET AL.: "Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator", NAT. BIOTECHNOL., vol. 35, 2017, pages 647 - 652, XP055540971, DOI: 10.1038/nbt.3865
S.H. HOS.W. HUANGC.Y. CHENT. HASUNUMAA. KONDO ET AL.: "Bioethanol production using carbohydrate-rich microalgae biomass as feedstock", BIORESOUR. TECHNOL., vol. 135, 2013, pages 191 - 198, XP028579618, DOI: 10.1016/j.biortech.2012.10.015
G.E. LAKATOSK. RANGLOVAJ. C. MANOELT. GRIVALSKYJ. KOPECKY ET AL.: "Bioethanol production from microalgae polysaccharides", FOLIA MICROBIOL. (PRAHA)., 2019
S. MCCUSKERP.R. BUFFZ. YUA.J FASCETTI: "Amino acid content of selected plant, algae and insect species: a search for alternative protein sources for use in pet foods", J. NUTR. SCI., vol. 3, 2014, pages e39
G. GUTIERREZ-SALMEANL. FABILA-CASTILLOG. CHAMORRO-CEVALLOS: "Nutritional and toxicological aspects of Spirulina (Arthrospira", NUTR. HOSP., vol. 32, 2015, pages 34 - 40
E.T. ALORIO.O. BABALOLA: "Microbial inoculants for improving crop quality and human health in Africa", FRONT. MICROBIOL., vol. 9, 2018, pages 2213
M.I. KHANJ. H. SHINJ. D. KIM: "The promising future of microalgae: current status, challenges and optimization of a sustainable and renewable industry for biofuels, feed and other products", MICROB. CELL FACT., vol. 17, 2018, pages 36
A.K. SINGHM.P. SINGH: "Importance of algae as a potential source of biofuel", CELL MOL. BIOL. (NOISY-LE-GRAND, vol. 60, 2014, pages 106 - 109
Y. HARAGUCHIY. KAGAWAK. SAKAGUCHIK. MATSUURAT. SHIMIZU ET AL.: "Thicker three-dimensional tissue from a ''symbiotic recycling system'' combining mammalian cells and algae", SCI. REP., vol. 7, 2017, pages 41594
Y. HARAGUCHIW. SEKINET. SHIMIZUM. YAMATOS. MIYOSHI, A. ET AL.: "Development of a new assay system for evaluating the permeability of various substances through three-dimensional tissue", TISSUE ENG. PART C METHODS., vol. 16, 2010, pages 685 - 692
Y. HARAGUCHIT. SHIMIZUT. SASAGAWAH. SEKINEK. SAKAGUCHI ET AL.: "Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro", NAT. PROTOC., vol. 7, 2012, pages 850 - 858
E.W. BECKER: "Micro-algae as a source of protein", BIOTECHNOL. ADV., vol. 25, 2007, pages 207 - 210, XP005862318, DOI: 10.1016/j.biotechadv.2006.11.002
P. SPOLAOREC. JOANNIS-CASSANE. DURANA. ISAMBERT: "Commercial applications of microalgae", J. BIOSCI. BIOENG., vol. 101, 2006, pages 87 - 96
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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