Title:
PROTEIN MATRIX MICROLENS ARRAY DIFFRACTION DEVICE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/052076
Kind Code:
A1
Abstract:
Disclosed are a protein matrix microlens array diffraction device (2) and a preparation method therefor, belonging to the technical field of biological detection apparatuses. A matrix of the protein matrix microlens array diffraction device (2) is a protein crystal, and a microlens-shaped bulge array is processed on a surface, where the side of the maximum length L is located, of the protein crystal. The protein matrix microlens array diffraction device (2) converts a measured quantity into physical quantities, such as the shape, the distribution and the spacing of a diffraction pattern, that are easier to measure, such that the detection precision and the flexibility are improved. According to the preparation method for the protein matrix microlens array diffractive device (2), the protein single crystal serves as the matrix of the microlens array diffractive device (2), such that the protein matrix microlens array diffractive device has a more stable solution environment, a longer service life and a wider range of applications. A method for processing the microlens array uses femtosecond laser processing, and micro-bulges are directly formed, such that processing is simple and easy, and the amount of thermal damage is small.
Inventors:
JIANG LAN (CN)
YAN JIANFENG (CN)
YU JIACHEN (CN)
YAN JIANFENG (CN)
YU JIACHEN (CN)
Application Number:
PCT/CN2020/109237
Publication Date:
March 25, 2021
Filing Date:
August 14, 2020
Export Citation:
Assignee:
UNIV TSINGHUA (CN)
International Classes:
G01N21/01; G02B1/04; G02B3/00
Domestic Patent References:
| WO2008118211A2 | 2008-10-02 |
Foreign References:
| CN110703372A | 2020-01-17 | |||
| CN110238530A | 2019-09-17 | |||
| CN109633795A | 2019-04-16 | |||
| CN104923919A | 2015-09-23 | |||
| CN108318485A | 2018-07-24 |
Other References:
ANTONOV I., BASS F., KAGANOVSKII YU., ROSENBLUH M., LIPOVSKII A.: "Fabrication of microlenses in Ag-doped glasses by a focused continuous wave laser beam", JOURNAL OF APPLIED PHYSICS, AMERICAN INSTITUTE OF PHYSICS, US, vol. 93, no. 5, 1 March 2003 (2003-03-01), US, pages 2343 - 2348, XP012059080, ISSN: 0021-8979, DOI: 10.1063/1.1540724
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)
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