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Patent Searching and Data


Title:
PROTEIN MOLECULE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/221135
Kind Code:
A1
Abstract:
Provided is a protein molecule and the use thereof. The protein molecule comprises IL12a or a functional fragment thereof, IL12b or a functional fragment thereof, a first factor and a second factor, wherein the first factor and the second factor are independently selected from the group of IL2, GMCSF, IL7, IL15, IL21 and FLT3L, and IL12a or the functional fragment thereof, IL12b or the functional fragment thereof, the first factor and the second factor are on the same polypeptide chain. The protein molecule can be used for treating tumors.

Inventors:
ZHANG JINYU (CN)
Application Number:
PCT/CN2020/086751
Publication Date:
November 05, 2020
Filing Date:
April 24, 2020
Export Citation:
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Assignee:
ZHANG JINYU (CN)
International Classes:
C07K19/00; A61K38/16; A61P35/00; C12N15/09
Foreign References:
CN1382158A2002-11-27
Other References:
WEN, QIAN ET AL.: "Fusion Cytokine IL -2-GMCSF Enhances Anticancer Immune Responses through Promoting Cell - Cell Interactions", JOURNAL OF TRANSLATIONAL MEDICINE, vol. 14, 31 December 2016 (2016-12-31), XP055382486, DOI: 10.1186/s12967-016-0799-7
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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