Title:
PTFE TUBULAR COVERED STENT AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/193576
Kind Code:
A1
Abstract:
A preparation method for a polytetrafluoroethylene (PTFE) tubular covered stent comprising: S1, using a braided tube sleeved on the outside of a metal mandrel as a receiving apparatus, and preparing a PTFE/polyethylene oxide (PEO) tubular fiber membrane; S2, after drying the PTFE/PEO tubular fiber membrane, sintering for 5-15 minutes at 360-400 °C; S3, providing a metal stent, coating a surface thereof with a polyurethane (TPU) adhesive, and then sleeving the tubular PTFE fiber membrane on the metal stent, placing in water to remove N, N-dimethylformamide (DMF), and allowing the TPU to cure; subsequently, taking out the metal stent, drying, sleeving a heat shrink tube on the outside of the tubular PTFE fiber membrane, and raising the temperature, causing the tubular PTFE fiber membrane to shrink, so as to be united more tightly with the metal stent, and thereby obtaining a PTFE tubular covered stent. The PTFE tubular covered stent has good mechanical properties, water permeability, and blood compatibility, has a hemolytic rate under than 5%, can support cell adhesion and proliferation of human umbilical vein endothelial cells (HUVECs), and has no cytotoxicity.
Inventors:
ZHAO HUIJING (CN)
LUO YU (CN)
MENG KAI (CN)
ZHANG KEQIN (CN)
GONG XIAOYAN (CN)
XUE ZHIHENG (CN)
LIU HAO (CN)
LUO YU (CN)
MENG KAI (CN)
ZHANG KEQIN (CN)
GONG XIAOYAN (CN)
XUE ZHIHENG (CN)
LIU HAO (CN)
Application Number:
PCT/CN2021/118144
Publication Date:
September 22, 2022
Filing Date:
September 14, 2021
Export Citation:
Assignee:
UNIV SOOCHOW (CN)
SUZHOU INNOMED MEDICAL DEVICE CO LTD (CN)
SUZHOU INNOMED MEDICAL DEVICE CO LTD (CN)
International Classes:
D04H1/728; D01D5/00; D04H1/76; D06C7/00
Foreign References:
| CN113151980A | 2021-07-23 | |||
| CN103561682A | 2014-02-05 | |||
| US20140074225A1 | 2014-03-13 | |||
| CN111388763A | 2020-07-10 | |||
| CN101168073A | 2008-04-30 | |||
| CN107872968A | 2018-04-03 | |||
| CN104842560A | 2015-08-19 | |||
| CN102430157A | 2012-05-02 |
Attorney, Agent or Firm:
CENTRAL SOUTH WELL INTELLECTUAL PROPERTY OFFICE (CN)
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