Title:
PYRAZOLOPYRAZINE-LINKED TRICYCLIC COMPOUND AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/156765
Kind Code:
A1
Abstract:
Disclosed is a pyrazolopyrazine-linked tricyclic compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The compound has inhibitory activity on protein tyrosine phosphatase SHP2 and can be used to treat diseases related to SHP2, such as lung cancer.
Inventors:
FU ZHIFEI (CN)
LUO MIAORONG (CN)
SHUAI BIN (CN)
ZHANG YANG (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
LUO MIAORONG (CN)
SHUAI BIN (CN)
ZHANG YANG (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2022/073167
Publication Date:
July 28, 2022
Filing Date:
January 21, 2022
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D487/04; A61K31/4985; A61P35/00; C07D491/107; C07D491/20
Domestic Patent References:
WO2019183367A1 | 2019-09-26 | |||
WO2021148010A1 | 2021-07-29 | |||
WO2018172984A1 | 2018-09-27 | |||
WO2016203404A1 | 2016-12-22 |
Foreign References:
CN111138412A | 2020-05-12 | |||
CN111704611A | 2020-09-25 |
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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