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Patent Searching and Data


Title:
PYRIDAZINONE COMPOUNDS WHICH MODULATE MUTANT PROTEINS FOR TREATING RESPIRATORY DISEASES
Document Type and Number:
WIPO Patent Application WO/2024/040350
Kind Code:
A8
Abstract:
The present disclosure relates to pyridazinone compound of the Formula (I) for the treatment of respiratory diseases, such as, chronic obstructive pulmonary disease (COPD), cystic fibrosis, cancer, Long QT syndrome or Dravet syndrome, which arise as a result of mis-folded or mis-shaped proteins.

Inventors:
BEAR CHRISTINE E (CA)
ECKFORD PAUL DAVID WILLIAM (CA)
LI CANHUI (CA)
RAMJEESINGH MOHABIR (CA)
HUAN LING-JUN (CA)
TANJALA ADRIAN (CA)
JIANG JIA XIN (CA)
PAONE DANIEL VINCENT (US)
BUSCH-PETERSEN JAKOB (CH)
Application Number:
PCT/CA2023/051122
Publication Date:
June 06, 2024
Filing Date:
August 24, 2023
Export Citation:
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Assignee:
HOSPITAL FOR SICK CHILDREN (CA)
International Classes:
C07D237/20; A61K31/501; A61K31/5377; A61P11/00; C07D401/04; C07D403/04
Attorney, Agent or Firm:
BERESKIN & PARR LLP/S.E.N.C.R.L., S.R.L. (CA)
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