Title:
PYRIDYL-SUBSTITUTED PORPHYRIN COMPOUNDS AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO2005097123
Kind Code:
A3
Abstract:
The present invention relates to Pyridyl-Substituted Porphyrin Compounds, compositions comprising an effective amount of a Pyridyl-Substituted Porphyrin Compound and methods for treating or preventing injury due to exposure to a reactive species, erectile dysfunction due to surgery, lung disease, hyperoxia, neurodegenerative disease, liver disease, myocardial damage during cardioplegia, an inflammatory condition, a reperfusion injury, an ischemic condition, a cardiovascular disease, diabetes, a diabetic complication, cancer, a side effect of cancer chemotherapy, or a radiation-induced injury, or to prolong the half-life of an oxidation-prone compound, comprising administering to a subject in need thereof an effective amount of a Pyridyl-Substituted Porphyrin Compound.
Inventors:
WILLIAMS WILLIAM (US)
SOUTHAN GARRY (US)
SZABO CSABA (US)
SOUTHAN GARRY (US)
SZABO CSABA (US)
Application Number:
PCT/US2005/010167
Publication Date:
December 22, 2005
Filing Date:
March 25, 2005
Export Citation:
Assignee:
INOTEK PHARMACEUTICALS CORP (US)
WILLIAMS WILLIAM (US)
SOUTHAN GARRY (US)
SZABO CSABA (US)
WILLIAMS WILLIAM (US)
SOUTHAN GARRY (US)
SZABO CSABA (US)
International Classes:
A61B5/055; A61B10/00; A61K31/40; A61K31/444; A61K31/555; C07B47/00; C07D487/22; C07F13/00; C07F15/02; (IPC1-7): A61B5/055; A61B10/00; C07B47/00; C07F5/10; A61K31/555; A61K31/40
Domestic Patent References:
| WO1999023097A1 | 1999-05-14 |
Foreign References:
| US6448239B1 | 2002-09-10 | |||
| US20030086916A1 | 2003-05-08 |
Other References:
See also references of EP 1740094A4
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