Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PYRIMIDINE DERIVATIVE, METHOD OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME AS EFFECTIVE COMPONENT
Document Type and Number:
WIPO Patent Application WO/2021/075691
Kind Code:
A1
Abstract:
The present invention relates to a pyrimidine derivative, a method of preparing same, and a pharmaceutical composition for preventing or treating cancer, comprising the pyrimidine derivative as an effective component, wherein the derivative exhibits a relatively weak inhibitory effect on EGFR activity with respect to wild-type EGFR while exhibiting a high inhibitory effect with respect to EGFR mutations, and thus can be effectively used for the treatment of cancer with EGFR mutations.

Inventors:
LEE KWANGHO (KR)
CHO BYOUNG CHUL (KR)
DUGGIRALA KRISHNA BABU (KR)
CHOI GILDON (KR)
YUN JIYEON (KR)
PARK CHAE WON (KR)
CHAE CHONG HAK (KR)
JUNG MYOUNG EUN (KR)
Application Number:
PCT/KR2020/010657
Publication Date:
April 22, 2021
Filing Date:
August 12, 2020
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOREA RES INST CHEMICAL TECH (KR)
International Classes:
C07D239/48; A23L33/10; A61K31/505; A61K31/5377; A61P35/00; C07D401/12
Domestic Patent References:
WO2017101803A12017-06-22
Foreign References:
KR20170118681A2017-10-25
CN106187915A2016-12-07
KR20190108079A2019-09-23
CN105503827A2016-04-20
Attorney, Agent or Firm:
LEE, Won Hee (KR)
Download PDF: