Title:
PYRROLO HETEROARYL DERIVATIVE OR CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/058027
Kind Code:
A1
Abstract:
A pyrrolo heteroaryl derivative or a conjugate thereof, a preparation method therefor and an application thereof. Specifically, a compound represented by general formula (D) or a ligand-drug conjugate thereof, a preparation method therefor, and an application of the ligand-drug conjugate and a pharmaceutical composition thereof in the preparation of a drug for the treatment of cancer or viral infectious diseases.
Inventors:
XU JIANYAN (CN)
ZHANG YING (CN)
CAI XIAOFENG (CN)
ZHANG ZHE (CN)
LIANG JINDONG (CN)
HE FENG (CN)
TAO WEIKANG (CN)
ZHANG YING (CN)
CAI XIAOFENG (CN)
ZHANG ZHE (CN)
LIANG JINDONG (CN)
HE FENG (CN)
TAO WEIKANG (CN)
Application Number:
PCT/CN2020/118837
Publication Date:
April 01, 2021
Filing Date:
September 29, 2020
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D487/04; A61K31/519; A61K31/5377; A61P1/16; A61P31/12; A61P31/14; A61P31/20; A61P35/00
Domestic Patent References:
| WO2019035971A1 | 2019-02-21 | |||
| WO2018210298A1 | 2018-11-22 | |||
| WO2015036044A1 | 2015-03-19 | |||
| WO2017188287A1 | 2017-11-02 |
Foreign References:
| CN110317202A | 2019-10-11 | |||
| CN110372703A | 2019-10-25 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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