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Title:
QUINOLINE DERIVATIVE FOR TREATING BRAIN TUMOR
Document Type and Number:
WIPO Patent Application WO/2020/057536
Kind Code:
A1
Abstract:
A quinoline derivative for treating a brain tumor. The compound I or a pharmaceutically acceptable salt thereof can be used to treat a metastatic brain tumor and is especially effective for a patient having a metastatic brain tumor from lung cancer .

Inventors:
WANG SHANCHUN (CN)
QIAN WENJUAN (CN)
LU QIN (CN)
XU HONGJIANG (CN)
YU DING (CN)
WANG XUNQIANG (CN)
PENG BANGAN (CN)
LIU LU (CN)
DAI JIE (CN)
Application Number:
PCT/CN2019/106379
Publication Date:
March 26, 2020
Filing Date:
September 18, 2019
Export Citation:
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Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
A61K31/4709; A61P35/04
Domestic Patent References:
WO2016091168A12016-06-16
WO2016091165A12016-06-16
WO2016091167A12016-06-16
Foreign References:
CN107771078A2018-03-06
CN103304572A2013-09-18
Other References:
HAN B.: "Anlotinib as a third-line therapy in patients with refractory advanced non-small- cell lung cancer: a multicentre, randomised phase II trial (ALTER0302", BRITISH JOURNAL OF CANCER, vol. 118, no. 5, 13 February 2018 (2018-02-13), pages 654 - 661, XP055695984, DOI: 10.1038/bjc.2017.478
LIU, ZHIHUA ET AL.: "Clinical Analysis of tyrosine Kinase Inhibitors in the Treatment of Brain Metastases of Non-Small Cell Lung Cancer", PROCEEDINGS OF THE THIRD ACADEMIC CONFERENCE 2012 JINAN INT. FORUM OF RADIATION ONCOLOGY, 1 May 2012 (2012-05-01), pages 226
Attorney, Agent or Firm:
NANJING TIANHUA PATENT AGENT CO., LTD. (CN)
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