Title:
RADIATION DAMAGE PROTECTIVE AGENT
Document Type and Number:
WIPO Patent Application WO/2018/124067
Kind Code:
A1
Abstract:
The present application provides: a radiation damage protective agent characterized by containing, as an active ingredient, hydrogen gas for treating or alleviating radiation damage suffered by a human patient who has experienced radiation exposure or who has undergone or is undergoing radiation therapy, the hydrogen gas being contained in a concentration of 18.5% by volume or less in a high-pressure capsule that exceeds standard atmospheric pressure; and a high-pressure capsule for administering a hydrogen gas treatment agent such as a radiation damage protective agent to patients, including humans.
Inventors:
AOKI YUKIMASA (JP)
HIRANO SHINICHI (JP)
SATO BUNPEI (JP)
KUROKAWA RYOSUKE (JP)
HIRANO SHINICHI (JP)
SATO BUNPEI (JP)
KUROKAWA RYOSUKE (JP)
Application Number:
PCT/JP2017/046633
Publication Date:
July 05, 2018
Filing Date:
December 26, 2017
Export Citation:
Assignee:
MIZ COMPANY LTD (JP)
INCORPORATED MEDICAL INST YUKOKAI (JP)
INCORPORATED MEDICAL INST YUKOKAI (JP)
International Classes:
A61K33/00; A61G10/02; A61H33/14; A61P7/00; A61P35/00; A61P39/06
Domestic Patent References:
| WO2008013163A1 | 2008-01-31 |
Foreign References:
| JP6133526B1 | 2017-05-24 |
Other References:
WATANABE, SADAHIRO, NIAD-QE, STUDY ON PROTECTION EFFECT OF 1.3% HYDROGEN GAS USING RADIATION SKIN FAILURE RAT MODEL, February 2016 (2016-02-01), Retrieved from the Internet [retrieved on 20180205]
TERASAKI, YASUHIRO ET AL.: "Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress", AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, vol. 301, no. 4, October 2011 (2011-10-01), pages 415 - 426, XP055515171, Retrieved from the Internet [retrieved on 20180204]
TERASAKI, YASUHIRO ET AL.: "Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress", AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, vol. 301, no. 4, October 2011 (2011-10-01), pages 415 - 426, XP055515171, Retrieved from the Internet
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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