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Title:
RAPID NON-DESTRUCTIVE TISSUE BIOPSY METHOD AND TECHNIQUE FOR LARGE AREA RESOLUTION OF MICROSTRUCTURE BASED ON SPATIAL FREQUENCY DOMAIN MODULATION
Document Type and Number:
WIPO Patent Application WO/2017/166082
Kind Code:
A1
Abstract:
Disclosed is a rapid non-destructive tissue biopsy method for large area resolution of a microstructure based on spatial frequency domain modulation. The method comprises the steps of: 1. controlling a light source to output multiple spatially modulated light stripe patterns of different frequencies to a tissue sample; 2. repeatedly collecting, by means of a CCD, the intensity of reflected light after said light is scattered by the tissue sample; 3. analyzing and processing the collected intensity data of the reflected light; 4. demodulating the data into an AC component, a DC component and a modulation transfer function using a standard three-phase shift method, an SSMD demodulation method or the like, wherein the AC component and the DC component have different frequencies; and 5. obtaining a scattering structural index (SSI).

Inventors:
XU MIN (US)
ZENG BIXIN (CN)
LIN WEIHAO (CN)
CAO ZILI (CN)
Application Number:
PCT/CN2016/077785
Publication Date:
October 05, 2017
Filing Date:
March 30, 2016
Export Citation:
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Assignee:
UNIV WENZHOU MEDICAL (CN)
International Classes:
G01N21/49
Domestic Patent References:
WO2015105780A12015-07-16
Foreign References:
CN102883658A2013-01-16
CN105300928A2016-02-03
CN105245761A2016-01-13
CN105190308A2015-12-23
Attorney, Agent or Firm:
WENZHOU JINOU PATENT LAW OFFICE (GENERAL PARTNERSHIP) (CN)
温州金瓯专利事务所(普通合伙) (CN)
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