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Title:
RAT RECEPTOR TYROSINE KINASE, KDR
Document Type and Number:
WIPO Patent Application WO2004070004
Kind Code:
A3
Abstract:
An isolated nucleic acid molecule encoding an optimized rat receptor type tyrosine kinase, KDR, is disclosed. The isolation of this KDR cDNA sequence results in disclosure of purified forms of rat KDR protein, recombinant vectors and recombinant hosts which express rat KDR.

Inventors:
THOMAS KENNETH A JR (US)
PAN BO-SHENG (US)
MCGAUGHEY GEORGIA B (US)
Application Number:
PCT/US2004/001928
Publication Date:
December 22, 2005
Filing Date:
January 23, 2004
Export Citation:
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Assignee:
MERCK & CO INC (US)
THOMAS KENNETH A JR (US)
PAN BO-SHENG (US)
MCGAUGHEY GEORGIA B (US)
International Classes:
C07H21/04; C07K14/705; C07K19/00; C12N1/00; C12N1/20; C12N5/06; C12N9/12; C12N15/00; C12N15/12; C12N15/54; C12N15/62; C12N15/63; C12P21/02; C12Q1/48; G01N33/566; C12N; (IPC1-7): C12N9/12; C07H21/04; C12N1/20; C12N5/06; C12N15/00; C12N15/54; C12N15/63; C12P21/02
Domestic Patent References:
WO1993010136A11993-05-27
Foreign References:
US6872699B22005-03-29
Other References:
DATABASE GENBANK [online] 13 July 2000 (2000-07-13), WEN ET AL, XP002992922, Database accession no. (O08775)
HANKS ET AL: "The protein kinase family: Conserved features and deduced phylogeny of catalytic domains.", SCIENCE., vol. 241, July 1988 (1988-07-01), pages 42 - 52, XP002933128
See also references of EP 1590436A4
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