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Patent Searching and Data


Title:
RECOMBINANT-PHAGE-BASED CONTAINER FOR STEM CELL CULTURE, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/241781
Kind Code:
A1
Abstract:
The present invention relates to a recombinant-phage-based container for a stem cell culture, and a use thereof. More specifically, provided are: a recombinant-phage-based container for a stem cell culture, on which cysteamine and a recombinant phage displaying a cell delivery peptide on the coat protein are coated; and a preparation method therefor. According to the present invention, a recombinant-phage-based container for a stem cell culture, of the present invention, provides a physical and mechanical niche environment created by the formation of a nanofibrous structure of the phage and promotes an increase in the physiological activity of target cells so as to help in tissue regeneration, and thus can be usable as an excellent therapeutic agent for corresponding diseases.

Inventors:
KWON SANG MO (KR)
JANG WOONG BI (KR)
LIM HYE JI (KR)
Application Number:
PCT/KR2020/006920
Publication Date:
December 02, 2021
Filing Date:
May 28, 2020
Export Citation:
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Assignee:
NAT UNIV PUSAN IND UNIV COOP FOUND (KR)
International Classes:
C12M1/12; C07C323/25; C12N5/077; C12N7/00
Foreign References:
KR101825458B12018-02-05
KR20120082626A2012-07-24
KR20180085698A2018-07-27
Other References:
STAQUICINI, F.I. ; SIDMAN, R.L. ; ARAP, W. ; PASQUALINI, R.: "Phage display technology for stem cell delivery and systemic therapy", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER, AMSTERDAM , NL, vol. 62, no. 12, 30 September 2010 (2010-09-30), Amsterdam , NL , pages 1213 - 1216, XP027509890, ISSN: 0169-409X, DOI: 10.1016/j.addr.2010.09.014
CONG ZHOU, JIALI KANG, XIAOXIA WANG, WEI WEI, WENYAN JIANG: "Phage display screening identifies a novel peptide to suppress ovarian cancer cells in vitro and in vivo in mouse models", BMC CANCER, vol. 15, no. 1, 1 December 2015 (2015-12-01), XP055347990, DOI: 10.1186/s12885-015-1891-8
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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