Title:
REDUCTION-TRIGGERED ANTIBACTERIAL SIDEROMYCINS
Document Type and Number:
WIPO Patent Application WO/2015/061630
Kind Code:
A3
Abstract:
A compound is provided, comprising: an Fe(III)-binding or an Fe(III)-bound siderophore; one or more optional linker covalently bound to the siderophore; a drug; and an Fe(III) to Fe(II) reduction triggered linker bound to the drug and the linker or, if no linker is present, then bound to the drug and the siderophore. Compositions and methods including the compound are also provided.
More Like This:
| JP2000510113 | [Title of Invention] Treatment of Asthma with TNFR-Ig |
| WO/2008/105514 | MULTIBRANCHED POLYOXYALKYLENE DERIVATIVE |
| WO/1998/034647 | ARGININE SILICATE INOSITOL COMPLEX AND USE THEREOF |
Inventors:
MILLER MARVIN J (US)
JI CHENG (US)
JI CHENG (US)
Application Number:
PCT/US2014/062069
Publication Date:
October 29, 2015
Filing Date:
October 23, 2014
Export Citation:
Assignee:
MILLER MARVIN J (US)
JI CHENG (US)
JI CHENG (US)
International Classes:
A61K47/48; A61K31/43; C07D499/48
Domestic Patent References:
| WO2012167368A1 | 2012-12-13 |
Other References:
SPRINGER, ELIZABETH., MASTER OF SCIENCE DISSERTATION, April 2013 (2013-04-01)
Attorney, Agent or Firm:
PIKE, John K. et al. (1000 Potomac St. NW,Suite 20, Washington District of Columbia, US)
Download PDF:
Previous Patent: DATA STORAGE DEVICE SUPPORTING ACCELERATED DATABASE OPERATIONS
Next Patent: COLOR STANDARDIZATION FOR DIGITIZED HISTOLOGICAL IMAGES
Next Patent: COLOR STANDARDIZATION FOR DIGITIZED HISTOLOGICAL IMAGES