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Title:
REPEATING DISACCHARIDE FOR OLIGOSACCHARIDE SYNTHESIS AND METHOD FOR PRODUCING OLIGOMER THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/054474
Kind Code:
A1
Abstract:
In the present invention, a disaccharide unit for synthesizing a useful sugar chain for suppressing the development of dystroglycanopathy is obtained and used to reconstitute a post-phosphoryl sugar chain. Provided are: a disaccharide derivative represented by formula (1) [wherein X1 is a leaving group or a protected hydroxyl group, Y1 is a carboxyl group, a hydroxymethyl group, or a precursor group thereof, and R1 to R5 are independently hydrogen or a protecting group for a hydroxyl group]; a production method for the same; and a method for producing an oligomer of the disaccharide derivative using the disaccharide derivative as an intermediate.

Inventors:
TAMURA JUNICHI (JP)
TAMURA TAKAHIRO (JP)
Application Number:
PCT/JP2020/035624
Publication Date:
March 25, 2021
Filing Date:
September 18, 2020
Export Citation:
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Assignee:
NAT UNIV CORP TOTTORI UNIV (JP)
International Classes:
C07H1/00; C07H7/033; C07H15/04; A61K31/715; A61P21/04
Domestic Patent References:
WO2019136399A12019-07-11
Other References:
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TAMURA, T. ET AL.: "Stereo-and regioselectiev Synthesis of 0-Mannosyl Glycan Containing Matriglycan and a part of Tandem Ribitol Phosphate", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 85, 15 September 2020 (2020-09-15), pages 12935 - 12946, XP055808035
Attorney, Agent or Firm:
MIYOSHI Hidekazu et al. (JP)
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