Title:
RESERVOIR FOR CARDIOPLEGIC SOLUTION CONTAINING BICARBONATE ION, AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2020/204170
Kind Code:
A1
Abstract:
Provided are a novel reservoir for a cardioplegic solution and a method for manufacturing the same. A reservoir for a cardioplegic solution provided with a multi-chamber container, a gas-impermeable outside package body in which the multi-chamber container is packaged, and an oxygen sensing agent and an oxygen scavenger which neither generates nor absorbs carbon dioxide gas, said oxygen sensing agent and oxygen scavenger being disposed within a space between the multi-chamber container and the outside package body, wherein: the multi-chamber container comprises at least a first chamber, a second chamber and a first partition wall separating these two chambers; the first chamber holds a first pharmaceutical solution; the second chamber holds a second pharmaceutical solution containing bicarbonate ion; the first pharmaceutical solution and/or the second pharmaceutical solution contain potassium ion; and the cardioplegic solution comprises the first pharmaceutical solution and the second pharmaceutical solution and contains 5-20 mEq/L of bicarbonate ion and 5-35 mEq/L of potassium ion. A method for manufacturing the reservoir.
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Inventors:
TOKUOKA SHOGO (JP)
TANAKA YASUSHIGE (JP)
INOUE SHIN-ICHI (JP)
MORI TOMOKO (JP)
TANAKA YASUSHIGE (JP)
INOUE SHIN-ICHI (JP)
MORI TOMOKO (JP)
Application Number:
PCT/JP2020/015352
Publication Date:
October 08, 2020
Filing Date:
April 03, 2020
Export Citation:
Assignee:
FUSO PHARMACEUTICAL IND (JP)
International Classes:
A61K9/08; A61J1/05; A61J1/10; B65D81/32
Domestic Patent References:
| WO2004108059A1 | 2004-12-16 |
Foreign References:
| JP2000308669A | 2000-11-07 | |||
| JP2000000462A | 2000-01-07 | |||
| JPH0549675A | 1993-03-02 | |||
| JP2007301205A | 2007-11-22 | |||
| JPH1134799A | 1999-02-09 | |||
| JP2000000462A | 2000-01-07 |
Other References:
MOCHIDA PHARMACEUTICAL: "Cardiac Surgery Cardioplegic and Myocardial-Protective Liquid: Miotecter forCoronary Vessels.", COMPOSITION/ATTRIBUTES, April 2015 (2015-04-01), pages 1 - 4, XP009532097
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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